Am J Psychiatry. 2014 Feb;171(2):187-94. doi: 10.1176/appi.ajp.2013.13020178.
The authors developed a computerized adaptive test for anxiety that decreases patient and clinician burden and increases measurement precision.
A total of 1,614 individuals with and without generalized anxiety disorder from a psychiatric clinic and community mental health center were recruited. The focus of the present study was the development of the Computerized Adaptive Testing-Anxiety Inventory (CAT-ANX). The Structured Clinical Interview for DSM-IV was used to obtain diagnostic classifications of generalized anxiety disorder and major depressive disorder.
An average of 12 items per subject was required to achieve a 0.3 standard error in the anxiety severity estimate and maintain a correlation of 0.94 with the total 431-item test score. CAT-ANX scores were strongly related to the probability of a generalized anxiety disorder diagnosis. Using both the Computerized Adaptive Testing-Depression Inventory and the CAT-ANX, comorbid major depressive disorder and generalized anxiety disorder can be accurately predicted.
Traditional measurement fixes the number of items but allows measurement uncertainty to vary. Computerized adaptive testing fixes measurement uncertainty and allows the number and content of items to vary, leading to a dramatic decrease in the number of items required for a fixed level of measurement uncertainty. Potential applications for inexpensive, efficient, and accurate screening of anxiety in primary care settings, clinical trials, psychiatric epidemiology, molecular genetics, children, and other cultures are discussed.
作者开发了一种用于焦虑症的计算机化自适应测试,以减少患者和临床医生的负担并提高测量精度。
共招募了来自精神病诊所和社区心理健康中心的 1614 名患有和不患有广泛性焦虑症的个体。本研究的重点是开发计算机化自适应测试-焦虑量表(CAT-ANX)。使用 DSM-IV 结构临床访谈获得广泛性焦虑症和重度抑郁症的诊断分类。
每个受试者平均需要 12 个项目,才能在焦虑严重程度估计中达到 0.3 个标准误差,并与 431 个项目的总测试分数保持 0.94 的相关性。CAT-ANX 分数与广泛性焦虑症诊断的可能性密切相关。同时使用计算机化自适应测试-抑郁量表和 CAT-ANX,可以准确预测合并的重度抑郁症和广泛性焦虑症。
传统的测量方法固定了项目的数量,但允许测量不确定性发生变化。计算机化自适应测试固定了测量不确定性,并允许项目的数量和内容发生变化,从而大大减少了固定测量不确定性水平所需的项目数量。讨论了在初级保健环境、临床试验、精神病流行病学、分子遗传学、儿童和其他文化中进行焦虑症的廉价、高效和准确筛查的潜在应用。