The University of Texas Health Science Center, USA.
J Clin Psychol. 2012 Jul;68(7):801-8. doi: 10.1002/jclp.21871. Epub 2012 May 23.
To examine the psychological sequelae following West Nile virus (WNV) infection among a large cohort of participants over an 8-year period.
We conducted a longitudinal study to assess mental health outcomes among a cohort of 171 WNV-positive participants in Houston, Texas.
We found 35% of participants met the Center for Epidemiologic Studies Depression scale definition for new onset clinical depression. Multivariate analysis found that severe depression was significantly associated with gender and physical disability (Barthel index score <100) at 5 years post-WNV infection.
Practitioners should be aware of depression as a possible outcome in patients who were infected with WNV and include this as a part of their routine assessment.
在长达 8 年的时间里，通过对一个大样本队列进行研究，探究西尼罗河病毒（WNV）感染后的心理后遗症。
我们开展了一项纵向研究，旨在评估德克萨斯州休斯顿市 171 名 WNV 阳性参与者的心理健康结果。
我们发现，35%的参与者符合流行病学研究中心抑郁量表对新发临床抑郁症的定义。多变量分析发现，5 年后，严重抑郁与性别和身体残疾（巴氏指数评分<100）显著相关。
临床医生应注意到，WNV 感染患者可能会出现抑郁，并将其作为常规评估的一部分。
