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牙本质敏感:过去、现在与未来。

Dentine sensitivity: past, present and future.

作者信息

Mantzourani Maria, Sharma Deepak

机构信息

Oral Care Scientific and Professional Affairs, Johnson & Johnson Consumer Services EAME Ltd, Foundation Park, Maidenhead, UK.

出版信息

J Dent. 2013 Jul;41 Suppl 4:S3-17. doi: 10.1016/S0300-5712(13)70002-2.

Abstract

OBJECTIVE

This review defines dentine sensitivity (DS), its prevalence, its aetiology, the mechanism(s) responsible for DS, its diagnosis and its treatment. The review then examines the modes of action of various treatments for DS including potassium salts, strontium salts, bioglasses, arginine/calcium carbonate and professional treatments such as adhesives and oxalates. The methods used to evaluate the various treatment modalities are discussed, including laboratory studies and randomised controlled clinical trials.

DATA SOURCES AND STUDY SELECTION

A literature search was conducted using PubMed, Ovid Medline and Cochrane reviews for information on DS and its treatments, as well as laboratory and clinical studies used to evaluate the efficacy of various DS treatments. With regard to efficacy of treatments for DS only reports of clinical studies that were randomised, controlled and blinded were reviewed. The authors offer new insights into the shortcomings of the recent systematic review of the use of oxalates for DS.

CONCLUSION

The authors introduce the concept of a novel desensitising mouthrinse containing 1.4% potassium oxalate: Listerine® Advanced Defence Sensitive mouthrinse. Readers of this supplement issue of the Journal of Dentistry are invited to review the significance of managing the clinical problem of DS. They are also invited to assess data from laboratory and randomised controlled clinical studies in order to understand the advantages offered by regular use of 1.4% potassium oxalate-containing mouthrinse, Listerine Advanced Defence Sensitive, in particular its resistance to daily erosive and/or abrasive challenges.

摘要

目的

本综述对牙本质敏感症(DS)进行了定义,阐述了其患病率、病因、引发DS的机制、诊断方法及治疗手段。随后,本综述探讨了多种DS治疗方法的作用方式,包括钾盐、锶盐、生物活性玻璃、精氨酸/碳酸钙以及诸如粘合剂和草酸盐等专业治疗方法。文中还讨论了用于评估各种治疗方式的方法,包括实验室研究和随机对照临床试验。

数据来源与研究选择

通过PubMed、Ovid Medline和Cochrane综述进行文献检索,以获取有关DS及其治疗的信息,以及用于评估各种DS治疗效果的实验室和临床研究。关于DS治疗的疗效,仅对随机、对照和盲法的临床研究报告进行了综述。作者对近期草酸盐用于DS的系统评价的不足之处提供了新的见解。

结论

作者介绍了一种新型脱敏漱口水的概念,即含有1.4%草酸钾的李施德林®高级防护敏感漱口水。本刊牙科杂志增刊的读者受邀审视解决DS临床问题的重要性。他们还受邀评估来自实验室和随机对照临床研究的数据,以了解定期使用含1.4%草酸钾的漱口水李施德林高级防护敏感漱口水所带来的优势,特别是其对日常侵蚀和/或磨损挑战的抵抗力。

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