Husain S Farhan, Ahmad Irshad, Shamsi Shariq
Department of Ilmul Saidla (Unani Pharmacy), National Institute of Unani Medicine, Bangalore, Karnataka, India.
Anc Sci Life. 2012 Jul;32(1):38-44. doi: 10.4103/0257-7941.113803.
Habb (Pill) is one of the important dosage forms of Unani system of medicine. A number of effective formulations are manufactured in form of Habb because of its various advantages. Out of these, Habbe Irqun Nisa (HI) is a popular anti-inflammatory formulation used in the treatment of Warame Mafasil (arthritis) and Irqun Nisa (sciatica). Nowadays, with increased incidence of these diseases many non-steroidal anti-inflammatory drugs (NSAIDs) are being used in their treatment. Owing to the adverse effects of these drugs, the use of herbal medicines is seen as a better alternative. The basic requirement for the development of Unani system of Medicine is the standardization of single and compound drugs. HI is mentioned in National Formulary of Unani Medicne and selected for the present study.
HI was prepared manually with the powder of crude drugs, passed through sieve no. 100 and mixed with 1% w/w of gum acacia in mucilage form. It was then dried at 60°C for 90 min and then tested for its standardization on different physicochemical parameters, e.g. organoleptic properties, pH values, moisture content, ash values, friability, hardness, weight variation, disintegration time, and thin layer chromatography (TLC).
The data evolved from this study will make it a validated product and will help in the quality control of other finished products in future research.
哈布（丸剂）是尤纳尼医学体系的重要剂型之一。由于其诸多优点，许多有效的制剂都制成哈布的形式。其中，哈贝·伊尔昆·尼萨（HI）是一种常用的抗炎制剂，用于治疗瓦拉梅·马法西尔（关节炎）和伊尔昆·尼萨（坐骨神经痛）。如今，随着这些疾病发病率的增加，许多非甾体抗炎药（NSAIDs）被用于治疗。由于这些药物的不良反应，草药被视为更好的替代品。尤纳尼医学体系发展的基本要求是单一是单一和复方药物的标准化。HI被列入《尤纳尼医学国家处方集》并被选用于本研究。
HI由粗药粉末手工制备，过100目筛，与1%w/w的阿拉伯胶黏液混合。然后在60°C下干燥90分钟，然后对其进行不同理化参数的标准化测试，如感官特性、pH值、水分含量、灰分、脆碎度、硬度、重量差异、崩解时间和薄层色谱（TLC）。
本研究得出的数据将使其成为一种经过验证的产品，并将有助于未来研究中其他成品的质量控制。
