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采用现代技术对复方尤纳尼草药制剂“Qurs-e-Luk”进行标准化。

Standardization of a compound Unani herbal formulation "Qurs-e-Luk" with modern techniques.

作者信息

Rasheed N M A, Gupta V C

机构信息

Central Research Institute of Unani Medicine, Opp.E.S.I. Hospital, A.G. Colony Road, Erragadda, Hyderabad-500838, India.

出版信息

Pharmacognosy Res. 2010 Jul;2(4):237-41. doi: 10.4103/0974-8490.69115.

DOI:10.4103/0974-8490.69115
PMID:21808574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3141134/
Abstract

BACKGROUND

With global realization that use of synthetic drugs is not safe on the long run, the medical fraternity at large is looking at alternatives from natural sources to combat diseases particularly those wherein conventional modern system of medicine has little to offer. On one hand, this realization has increased demand for herbal drugs and on the other hand need for quality standardization of these drugs has increased. Central Research Institute of Unani Medicine, Hyderabad, being engaged in multidisciplinary research in Unani Medicine, has taken up standardization of herbomineral drugs used in this system of medicine. One such drug "Qurs-e-Luk" that is widely used by the practitioners of this system in mobilizing and reducing body fat has been utilized for standardization by modern techniques, so as to ascertain its quality.

METHODS

The parameters which were carried out are pharmacognostic studies, physicochemical parameters, high-performance thin layer chromatography, microbial load, aflatoxins, heavy metals, and pesticidal residues revealing specific identities for the particular drug and to evaluate pharmacopoeial standards.

RESULTS AND CONCLUSION

Results suggest that the drug is safe for therapeutic use and its batch to batch identification for quality control is possible on the basis of present study.

摘要

背景

随着全球意识到长期使用合成药物不安全,广大医学界正在寻找天然来源的替代品来对抗疾病,尤其是那些传统现代医学几乎无能为力的疾病。一方面,这种认识增加了对草药药物的需求,另一方面,对这些药物进行质量标准化的需求也增加了。位于海得拉巴的尤纳尼医学中央研究所从事尤纳尼医学的多学科研究,已着手对该医学体系中使用的草药矿物药物进行标准化。该医学体系的从业者广泛使用的一种名为“Qurs-e-Luk”的药物,用于调动和减少体内脂肪,现已采用现代技术进行标准化,以确定其质量。

方法

所进行的参数包括生药学研究、理化参数、高效薄层色谱法、微生物负荷、黄曲霉毒素、重金属和农药残留,以揭示该特定药物的具体特性并评估药典标准。

结果与结论

结果表明,该药物用于治疗是安全的,并且根据本研究可以对其进行批次间质量控制鉴定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/97897198a28f/PR-2-237-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/a864db4a55ca/PR-2-237-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/d3541b51bb7b/PR-2-237-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/1483c1187cd8/PR-2-237-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/2b2832c4785d/PR-2-237-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/97897198a28f/PR-2-237-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/a864db4a55ca/PR-2-237-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/d3541b51bb7b/PR-2-237-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/1483c1187cd8/PR-2-237-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/2b2832c4785d/PR-2-237-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5764/3141134/97897198a28f/PR-2-237-g005.jpg

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