具有弥漫性大B细胞淋巴瘤（DLBCL）和黏膜相关淋巴组织淋巴瘤成分的原发性前列腺淋巴瘤。
Primary prostatic lymphoma with components of both diffuse large B-cell lymphoma (DLBCL) and MALT lymphoma.
作者信息
Petrakis G, Koletsa T, Karavasilis V, Rallis G, Bobos M, Karkavelas G, Kostopoulos I
机构信息
Department of Pathology, Medical School, Aristotle University of Thessaloniki, Greece.
出版信息
Hippokratia. 2012 Jan;16(1):86-9.
Although lymphomas involving the prostate gland are rare, they should always be considered in the differential diagnosis. We report a case of primary prostatic NHL in a 70-year-old man presented with hematuria and urinary obstructive symptoms. Routine laboratory tests were within normal limits and prostate-specific antigen (PSA) was 0,01 ng/ml. The patient underwent radical prostatectomy. Histologically, two different coexisting patterns of non-Hodgkin lymphoma, infiltrating the prostatic tissue, were identified. The diagnosis of diffuse large B-cell lymphoma (DLBCL) presenting with an associated low-grade lymphoma of MALT-type was confirmed by immunohistochemistry. The patient received chemotherapy without any complication and has been followed-up for 2 years since surgical resection with no recurrence. The clinicopathologic characteristics of prostatic lymphomas are discussed, while reviewing the current English-language literature.
尽管累及前列腺的淋巴瘤很罕见，但在鉴别诊断时应始终予以考虑。我们报告一例70岁男性原发性前列腺非霍奇金淋巴瘤，该患者表现为血尿和尿路梗阻症状。常规实验室检查结果正常，前列腺特异性抗原（PSA）为0.01 ng/ml。患者接受了根治性前列腺切除术。组织学检查发现，两种不同的非霍奇金淋巴瘤共存模式浸润了前列腺组织。免疫组织化学证实诊断为弥漫性大B细胞淋巴瘤（DLBCL）伴相关的MALT型低级别淋巴瘤。患者接受化疗，无任何并发症，自手术切除后已随访2年，无复发。在回顾当前英文文献的同时，讨论了前列腺淋巴瘤的临床病理特征。
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