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前列腺血液淋巴肿瘤:弥漫性大B细胞淋巴瘤病例报告。

Hematolymphoid tumor of prostate: Diffuse large B cell lymphoma case report.

作者信息

Ochirjav Enkhee, Tsedenbal Batchimeg, Enkhjargal Manduul, Mendbayar Erdenesaikhan, Sharkhuu Enkhtuya

机构信息

National Center for Pathology, Ulaanbaatar, Mongolia.

Nuclear Medicine Center, Second State Central Hospital of Mongolia, Ulaanbaatar, Mongolia.

出版信息

Urol Case Rep. 2023 Jul 5;50:102497. doi: 10.1016/j.eucr.2023.102497. eCollection 2023 Sep.

DOI:10.1016/j.eucr.2023.102497
PMID:37484192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10362163/
Abstract

Prostate lymphomas are very rare, with few reported cases in the literature. However, differential diagnoses should be considered. We report a hematolymphoid tumor of the prostate in a 67-year-old man who was admitted to the hospital with hematuria and obstructive urinary symptoms. The patient underwent a cystoscopy procedure to obtain a biopsy from the prostate with bipolar resection. Histologically, sheets of lymphoid tumor cells resembling non-Hodgkin lymphoma, infiltrated into the prostatic tissue, were identified. The diagnosis of diffuse large B-cell lymphoma was confirmed by immunohistochemistry. The clinicopathologic characteristics of prostatic lymphomas are discussed in the light review literature.

摘要

前列腺淋巴瘤非常罕见,文献报道的病例很少。然而,应考虑鉴别诊断。我们报告了一名67岁男性的前列腺血液淋巴肿瘤,该患者因血尿和梗阻性尿路症状入院。患者接受了膀胱镜检查,通过双极切除术从前列腺获取活检组织。组织学上,发现成片的类似非霍奇金淋巴瘤的淋巴肿瘤细胞浸润到前列腺组织中。免疫组织化学证实为弥漫性大B细胞淋巴瘤。结合文献综述讨论了前列腺淋巴瘤的临床病理特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9530/10362163/acfaecf18fc3/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9530/10362163/1c5d9ccc5476/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9530/10362163/fb772b670add/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9530/10362163/acfaecf18fc3/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9530/10362163/1c5d9ccc5476/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9530/10362163/fb772b670add/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9530/10362163/acfaecf18fc3/gr3.jpg

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引用本文的文献

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Clinical and prognostic factors guiding diagnosis and treatment of prostate diffuse large B-cell lymphoma.指导前列腺弥漫性大B细胞淋巴瘤诊断与治疗的临床及预后因素
Sci Rep. 2025 Apr 12;15(1):12594. doi: 10.1038/s41598-025-96315-w.

本文引用的文献

1
Unexpected discovery of prostatic diffuse large B-cell lymphoma after thulium laser vaporization in a patient with Waldenstrom macroglobulinemia.在一名患有华氏巨球蛋白血症的患者接受铥激光汽化术后意外发现前列腺弥漫性大B细胞淋巴瘤。
Quant Imaging Med Surg. 2022 Jan;12(1):862-867. doi: 10.21037/qims-20-1319.
2
Incidental and concurrent malignant lymphomas discovered at the time of prostatectomy and prostate biopsy: a study of 29 cases.前列腺切除术和前列腺活检时发现的偶然和并发恶性淋巴瘤:29例研究
Am J Surg Pathol. 2005 May;29(5):693-9. doi: 10.1097/01.pas.0000153122.65138.b1.
3
Malignant lymphoma involving the prostate: report of 62 cases.
累及前列腺的恶性淋巴瘤:62例报告。
Cancer. 1998 Aug 15;83(4):732-8. doi: 10.1002/(sici)1097-0142(19980815)83:4<732::aid-cncr15>3.0.co;2-t.