脂质密度的变化会诱导膜曲率。
Changes in lipid density induce membrane curvature.
作者信息
de Jesus Armando J, Kastelowitz Noah, Yin Hang
机构信息
Department of Chemistry & Biochemistry and the BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303, USA.
出版信息
RSC Adv. 2013 Sep 7;3(33):13622-13625. doi: 10.1039/C3RA42332H.
Abstract
Highly curved bilayer lipid membranes make up the shell of many intra- and extracellular compartments, including organelles and vesicles. Using all-atom molecular dynamics simulations, we show that increasing the density of lipids in the bilayer membrane can induce the membrane to form a curved shape.
摘要
高度弯曲的双层脂质膜构成了许多细胞内和细胞外区室的外壳，包括细胞器和囊泡。通过全原子分子动力学模拟，我们表明增加双层膜中脂质的密度可以诱导膜形成弯曲形状。
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