Gurtani Fatemeh Mostajeran, Fadaei Behrooz, Akbari Mojtaba
Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2013 Mar 6;2:20. doi: 10.4103/2277-9175.108004. Print 2013.
Peripartum hysterectomy is associated with significant morbidity and mortality. We determined the factors leading to and maternal mortality and morbidity rates among the women whose underwent peripartum hysterectomy in Iran.
This case-series study was conducted from March 2004 to March 2009 in the Department of Gynecology and Obstetrics at two central university hospitals (Azahra hospital and Shahid Beheshti Hospital) in Isfahan. Forty one women among 29,444 deliveries underwent peripartum hysterectomy. Women who had delivery before 24 weeks and a hysterectomy for other reasons like sterilizations were excluded. Incidence, indications and maternal complications including maternal death and urological, infectious and wound complications were evaluated after operation.
During the study period, the incidence of peripartum hysterectomy estimated about 1.39 per 1,000 deliveries. The maternal mortality rate was 17.07%. There was no statistical difference in mortality rates between referrals and non-referrals women (P = 0.6). Post-operative complications included infection (22%), bladder injuries (7.3%), urine retention (4.8%) and wound dehiscence (4.87%). The main indication was placenta accreta 28 (68.3%).
This study indicated the high rate of mortality among patients underwent peripartum hysterectomy. Evaluation of management during referring the patients and designing more studies to evaluate the mortality and morbidities are warranted.
围产期子宫切除术与显著的发病率和死亡率相关。我们确定了伊朗接受围产期子宫切除术的女性中导致死亡和发病的因素以及孕产妇死亡率和发病率。
本病例系列研究于2004年3月至2009年3月在伊斯法罕的两家中心大学医院(阿扎拉医院和沙希德·贝赫什提医院)的妇产科进行。在29444例分娩中有41名女性接受了围产期子宫切除术。排除孕周小于24周分娩以及因绝育等其他原因进行子宫切除术的女性。术后评估发病率、手术指征以及包括孕产妇死亡、泌尿系统、感染和伤口并发症在内的孕产妇并发症。
在研究期间,围产期子宫切除术的发病率估计约为每1000例分娩1.39例。孕产妇死亡率为17.07%。转诊和未转诊女性的死亡率无统计学差异(P = 0.6)。术后并发症包括感染(22%)、膀胱损伤(7.3%)、尿潴留(4.8%)和伤口裂开(4.87%)。主要手术指征是胎盘植入28例(68.3%)。
本研究表明接受围产期子宫切除术的患者死亡率较高。有必要评估患者转诊过程中的管理情况,并设计更多研究来评估死亡率和发病率。