Zigdon Hadar, Levin Liran
Department of Periodontology, School of Graduate Dentistry, Laboratory of Bone Repair, Rambam Health Care Campus, Hailfa, Israel.
Alpha Omegan. 2012 Spring-Summer;105(1-2):35-8.
Alveolar bone atrophy may occur due to trauma, malignancy and periodontal disease. Restoring the lost bone is crucial for the rehabilitation of the patient's functioning, phonetics and aesthetics. Currently the methods available for vertical bone augmentation prior to dental implant placement are rather limited. This paper describes present and future concepts of utilizing mesenchymal stem cells (MSC) as well as endothelial progenitor cells (EPC) for enhancing bone growth in severe atrophic cases. Stem/progenitor cell-based regenerative therapy may prove to be the best option to meet individual patient needs and open new horizons in periodontal, maxillofacial and implant surgery.
牙槽骨萎缩可能由于创伤、恶性肿瘤和牙周疾病而发生。恢复缺失的骨组织对于患者功能、语音和美观的康复至关重要。目前，在种植牙植入前进行垂直骨增量的可用方法相当有限。本文描述了利用间充质干细胞（MSC）以及内皮祖细胞（EPC）促进严重萎缩病例骨生长的当前和未来概念。基于干细胞/祖细胞的再生治疗可能被证明是满足个体患者需求并为牙周、颌面和种植牙手术开辟新视野的最佳选择。
