Mengistu Zuriyash, Chere Amsale
Department of Nursing, Faculty of Medicine, Addis Ababa University.
Ethiop Med J. 2012 Oct;50(4):355-61.
HIV/AIDS became a chronic illness since the introduction of Anti-Retroviral-Therapy which needs ongoing assessment for adherence to prevent treatment failure.
The objective of this study was to assess antiretroviral therapy adherence and its associated factors.
A cross-sectional quantitative study was conducted on 420 People Living With HIV/AIDS (PLWHA) who were attending Anti-Retroviral-Therapy clinic at Tikur Anbessa, Zewditu and St Paul's Hospitals from March to April 2009. Systematic random sampling technique was used to select the participants from their document. Then Data were collected, checked, categorized, coded and analyzed using SPSS 15.0 statistical package.
From the total 420 respondents, 244 (58.1%) were women. Among the respondents, 308 (73.3%) had adhered to Anti-Retroviral-Therapy (ART). Respondents who had good relationship with health care provider had 3.15 times more likely to adhere to ART compared to those who had poor relationship. Those who stated stigma and discrimination as a major problem were 81% less likely to adhere to ART compared to those who stated stigma and discrimination not to be a problem at all.
The findings of the study indicate that ART adherence rate to be low. The study also showed that Stigma and discrimination, and poor relationship with health care provider to be associated with low adherence. Based on the finding, keep away from stigmatization and discrimination, and enhancing good relationship need to be given attention for improving ART adherence.
自抗逆转录病毒疗法引入以来，艾滋病毒/艾滋病已成为一种慢性病，需要持续评估依从性以防止治疗失败。
本研究的目的是评估抗逆转录病毒疗法的依从性及其相关因素。
2009年3月至4月，对在提库尔·安贝萨、泽韦迪图和圣保罗医院抗逆转录病毒疗法诊所就诊的420名艾滋病毒/艾滋病感染者进行了一项横断面定量研究。采用系统随机抽样技术从他们的病历中选取参与者。然后使用SPSS 15.0统计软件包收集、检查、分类、编码和分析数据。
在420名受访者中，244名（58.1%）为女性。在受访者中，308名（73.3%）坚持接受抗逆转录病毒疗法（ART）。与医护人员关系良好的受访者坚持接受ART的可能性是关系不佳者的3.15倍。认为耻辱和歧视是主要问题的受访者坚持接受ART的可能性比认为根本不存在耻辱和歧视问题的受访者低81%。
研究结果表明抗逆转录病毒疗法的依从率较低。研究还表明，耻辱和歧视以及与医护人员的不良关系与低依从性有关。基于这些发现，为提高抗逆转录病毒疗法的依从性，需要关注避免耻辱和歧视以及加强良好关系。
