Shabzendedar Mahboobeh, Mazhari Fatemeh, Alami Maliheh, Talebi Maryam
Dental Material Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Pediatr Dent. 2013 Jul-Aug;35(4):329-32.
The study evaluated the effects of 3 percent sodium hypochlorite (NaOCl) and formocresol (FC) as pulp dressing agents in pulpotomized primary molars.
One hundred children between three and six years each with at least one primary mandibular second molar requiring pulpotomy were randomly allocated to two groups (of 50 each). All the teeth received stainless steel crown after conventional pulpotomy procedure with either NaOCI (applied for 15 second) or FC (applied for one minute). Clinical and radiographic signs/symptoms were blindly recorded at zero, six. and 12 months. The differences were statistically analyzed using the Fisher's exact test.
At six months, 100 percent clinical success was found with both NaOCl, and FC. Radiographic success rates for NaOCl were 98 percent and 92 percent at 6- and 12-month recalls respectively. FC group showed 94 percent and 93 percent radiographic success rates at the same periods respectively. There was no statistically significant difference between the groups.
NaOCl can be suggested as a pulpotomy agent for primary teeth pulpotomies. However further clinical studies with long-term follow-ups are needed to test the efficacy of NaOCl as a pulpotomy medicament in primary teeth.
本研究评估3%次氯酸钠(NaOCl)和甲醛甲酚(FC)作为乳牙活髓切断术牙髓消毒药物的效果。
100名3至6岁的儿童,每人至少有一颗需要进行活髓切断术的下颌乳第二磨牙,被随机分为两组(每组50人)。所有牙齿在常规活髓切断术后均戴上不锈钢冠,分别使用NaOCl(应用15秒)或FC(应用1分钟)。在0、6和12个月时,对临床和影像学的体征/症状进行盲法记录。使用Fisher精确检验对差异进行统计学分析。
在6个月时,NaOCl和FC的临床成功率均为100%。NaOCl在6个月和12个月复查时的影像学成功率分别为98%和92%。FC组在同一时期的影像学成功率分别为94%和93%。两组之间无统计学显著差异。
可推荐NaOCl作为乳牙活髓切断术的药物。然而,需要进一步的长期随访临床研究来测试NaOCl作为乳牙活髓切断术药物的疗效。