Kawada Tomoyuki, Otsuka Toshiaki
Department of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan.
Arch Environ Occup Health. 2014;69(1):55-61. doi: 10.1080/19338244.2012.732123.
A 3-year follow-up study of an occupational cohort was conducted to clarify the effect of the type of shift work on the risk of development of metabolic syndrome (MetS). The subjects were 1,677 Japanese male employees aged 36 to 57. Age, each component of MetS, serum uric acid, serum insulin, lifestyle factors, and occupational position were used for the analyses. The odds ratios (95% confidence intervals) of 2-shift work (n = 686) and 3-shift work (n = 99) against daytime work (n = 868) for the development of MetS, as defined by the National Cholesterol Education Program, were 1.43 (1.05, 1.95) and 0.72 (0.37, 1.41), respectively. When Japanese criteria were adopted for defining MetS, the corresponding odds ratios (95% confidence intervals) were 1.88 (1.29, 2.74) and 0.87 (0.39, 1.97), respectively. The results of the analyses suggested that 2-shift work was a risk factor for the development of metabolic syndrome.
开展了一项针对职业队列的3年随访研究，以阐明轮班工作类型对代谢综合征（MetS）发生风险的影响。研究对象为1677名年龄在36至57岁之间的日本男性员工。分析中使用了年龄、MetS的各个组成部分、血清尿酸、血清胰岛素、生活方式因素和职业地位。根据美国国家胆固醇教育计划定义的MetS，两班制工作（n = 686）和三班制工作（n = 99）相对于日班工作（n = 868）发生MetS的比值比（95%置信区间）分别为1.43（1.05，1.95）和0.72（0.37，1.41）。当采用日本的标准来定义MetS时，相应的比值比（95%置信区间）分别为1.88（1.29，2.74）和0.87（0.39，1.97）。分析结果表明，两班制工作是代谢综合征发生的一个风险因素。
