1 Department of Internal Medicine, Fundación de Investigación Biomédica, Hospital Universitario La Princesa , Madrid, Spain .
J Palliat Med. 2013 Sep;16(9):1102-7. doi: 10.1089/jpm.2013.0136. Epub 2013 Aug 9.
Spanish cultural perception of end-of-life decision making has started to change within a new legal framework.
The objective of this study was to describe how life-sustaining treatments (LST) were withheld or withdrawn in an intensive care unit (ICU), to determine the degree of agreement between physicians and patients' families on end-of-life decisions, and to compare our results to those of studies undergone before these legal changes.
This was an observational retrospective study.
SETTING/SUBJECTS: The setting and subjects were patients admitted to a medical and surgical ICU in a metropolitan tertiary care center from January 2002 to December 2009 whose LST had been withheld or withdrawn.
Study measurements included age and sex; comorbidities; functional status on admission; main diagnosis; SAPS II and APACHE II scores on admission; degree of agreement on end-of-life practices; and therapeutic interventions withheld or withdrawn and outcome.
A total of 371 of 6526 patients (5.7%) had LST withheld or withdrawn; 339 of these patients died in the ICU. Patients whose LST was withheld or withdrawn were older, had a high number of comorbidities, and were admitted with higher SAPS II and APACHE II scores than the general ICU population. Active treatments and basic support were discontinued in 212 patients (57%) and 100 patients (26.9%), respectively. An agreement between the staff and the patient's family was reached in 318 cases (85.7%). Families were not involved in 30 cases (8.1%).
Compared to prior studies, shared end-of-life decision making in the ICU has increased in recent years. Decisions to forgo treatments mainly involve advanced life support.
在新的法律框架下,西班牙人对临终决策的文化观念开始发生变化。
本研究旨在描述在重症监护病房(ICU)中如何停止或撤回生命维持治疗(LST),确定医生和患者家属在临终决策上的一致程度,并将我们的结果与这些法律变更之前进行的研究进行比较。
这是一项观察性回顾性研究。
地点/受试者:地点和受试者为 2002 年 1 月至 2009 年 12 月期间入住大都市三级护理中心的内科和外科 ICU 的患者,其 LST 被停止或撤回。
研究测量包括年龄和性别;合并症;入院时的功能状态;主要诊断;入院时的 SAPS II 和 APACHE II 评分;对临终实践的一致程度;以及停止或撤回的治疗干预措施和结果。
在 6526 名患者中,共有 371 名(5.7%)停止或撤回了 LST;其中 339 名患者在 ICU 中死亡。停止或撤回 LST 的患者年龄较大,合并症较多,入院时的 SAPS II 和 APACHE II 评分高于一般 ICU 人群。212 名患者(57%)和 100 名患者(26.9%)分别停止了积极治疗和基本支持。在 318 例(85.7%)病例中,工作人员与患者家属达成了一致意见。30 例(8.1%)家属未参与。
与之前的研究相比,近年来 ICU 中共同做出临终决策的比例有所增加。放弃治疗的决定主要涉及高级生命支持。