Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3-Kasumi, Minami-ku, Hiroshima City, Hiroshima 734-0037, Japan.
Thorac Surg Clin. 2013 Aug;23(3):301-11. doi: 10.1016/j.thorsurg.2013.04.003. Epub 2013 May 10.
Sublobar resection is a compromise for patients with insufficient lung function. Recently small lung cancers are usually detected at the early stage, but sublobar resection in patients who can tolerate lobectomy is not yet standard treatment. Although a few old studies showed higher rates of local recurrence and a poorer prognosis after sublobar resection compared with lobectomy, most have indicated promising outcomes after sublobar resection. Large-scale, randomized, controlled multicenter trials are ongoing in the United States and Japan, the results of which could create revolutionary changes in general thoracic surgery. This article reviews the literature on surgical outcomes of radical sublobar resection.
亚肺叶切除术是肺功能不足患者的一种妥协。最近，通常在早期阶段就能检测到小肺癌，但对于能够耐受肺叶切除术的患者，亚肺叶切除术尚不是标准治疗方法。尽管少数旧研究显示亚肺叶切除术后局部复发率和预后较肺叶切除术差，但大多数研究表明亚肺叶切除术后的结果有良好的前景。目前美国和日本正在进行大规模、随机、对照、多中心临床试验，其结果可能会给胸外科带来革命性的变化。本文综述了根治性亚肺叶切除术的手术结果的文献。
