Department of Chemistry, Tongji University, Shanghai 200092, PR China.
Org Biomol Chem. 2013 Sep 28;11(36):6008-12. doi: 10.1039/c3ob41218k.
An atom-efficient and transition metal-free approach to amides from the corresponding benzyl hydrocarbons through C-H and C-C bond cleavage has been developed. Mechanistic studies have shown that a DDQ-promoted cross-dehydrogenative coupling (CDC) reaction with subsequent oxidation and rearrangement are involved in this transformation.
通过 C-H 和 C-C 键的断裂，从相应的苄基烃高效、无过渡金属的方法合成酰胺已经被开发出来。机理研究表明，该转化涉及 DDQ 促进的交叉脱氢偶联（CDC）反应，随后是氧化和重排。
