Department of Preventive Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hněvotínská 3, 775 15, Olomouc, Czech Republic.
Parasitol Res. 2013 Oct;112(10):3661-4. doi: 10.1007/s00436-013-3554-5. Epub 2013 Aug 11.
In in vitro tests, skin repellent IR3535, applied in the form of the Diffusil H Prevental product in an aerosol bomb (active compound 20%), killed 100% of head lice (females and males) and nymphs 2 and 3, when directly sprayed at a dose of 0.94 mg of the active compound per square centimeter. Crawling lice exposed for 1 min on the filter paper impregnated by the same concentration showed no effort to suck blood 30 min after exposition. Twenty hours later, their mortality rate was 11 %. After the lice had been exposed for approximately 1 min (until they actively left the area) on 5 cm round areas of skin of test persons treated with the repellent at a mean total dose of 23.3 mg of active compound, they showed no effort to suck blood on the clean skin of other test person either immediately after exposure or 30 min later. Their mortality after 20 h ranged from 59 to 16%, depending on the time elapsed from skin treatment (10 min to 27 h).
在体外试验中，以气溶胶弹形式（活性成分 20%）施用的驱蚊剂 IR3535（Diffusil H Prevental 产品），当直接以每平方厘米 0.94 毫克活性化合物的剂量喷洒时，杀死了 100%的头虱（雌性和雄性）和 2 龄和 3 龄若虫。在滤纸上浸渍相同浓度的药剂后爬行的虱子暴露 1 分钟后，暴露 30 分钟后没有吸血的企图。20 小时后，它们的死亡率为 11%。在以 23.3 毫克活性化合物的平均总剂量处理过驱蚊剂的试验人员的 5 厘米圆形皮肤区域上，虱子大约暴露 1 分钟（直到它们主动离开该区域）后，它们立即或 30 分钟后在其他试验人员的干净皮肤上没有吸血的企图。20 小时后的死亡率在 59%至 16%之间，这取决于从皮肤处理（10 分钟至 27 小时）开始的时间。
