南非接受抗逆转录病毒疗法 (ART) 的患者中，饮酒情况、其他心理社会因素、结构因素与抗逆转录病毒疗法 (ART) 依从性之间的关联。
Associations between alcohol use, other psychosocial factors, structural factors and antiretroviral therapy (ART) adherence among South African ART recipients.
机构信息
Alcohol and Drug Abuse Research Unit, Medical Research Council, Private Bag X385, Pretoria, 0001, South Africa,
出版信息
AIDS Behav. 2014 Mar;18(3):519-24. doi: 10.1007/s10461-013-0583-0.
We examined whether alcohol use is associated with antiretroviral therapy (ART) adherence independently of structural and psychosocial factors among 304 male and female ART recipients in ART sites in Tshwane, South Africa. ART adherence was assessed by the CASE Adherence Index. Independent variables were demographic, structural, psycho-social, and alcohol use (AUDIT score) factors. In hierarchical multiple regression, demographic variables (Step 1) explained 4 % of variance in ART adherence (p ≤ 0.01). Variance explained increased to 16 % (p ≤ 0.001) after entering structural variables (Step 2); 19 % (p ≤ 0.001) after entering psychosocial variables (Step 3); and 24 % (p ≤ 0.001) after entering AUDIT score (Step 4). Alcohol use is independently associated with ART adherence.
我们研究了南非茨瓦内的艾滋病治疗点的 304 名男性和女性艾滋病治疗受者中，是否存在除结构和心理社会因素以外，酒精使用与抗逆转录病毒治疗（ART）依从性相关的情况。ART 依从性通过 CASE 依从性指数进行评估。自变量包括人口统计学、结构、心理社会和酒精使用（AUDIT 评分）因素。在分层多元回归中，人口统计学变量（第 1 步）解释了 ART 依从性的 4%（p ≤ 0.01）。进入结构变量（第 2 步）后，解释的方差增加到 16%（p ≤ 0.001）；进入心理社会变量（第 3 步）后，解释的方差增加到 19%（p ≤ 0.001）；进入 AUDIT 评分（第 4 步）后，解释的方差增加到 24%（p ≤ 0.001）。酒精使用与 ART 依从性独立相关。
Zotero 插件