Hasegawa Yumi, Okamoto Fumiki, Sugiura Yoshimi, Okamoto Yoshifumi, Hiraoka Takahiro, Oshika Tetsuro
Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Ibaraki - Japan.
Eur J Ophthalmol. 2014 Mar-Apr;24(2):235-41. doi: 10.5301/ejo.5000350. Epub 2013 Aug 7.
To determine the incidence of and risk factors for intraocular pressure (IOP) elevation in the immediate postoperative period after vitrectomy for various vitreoretinal disorders.
A prospective study was performed in 228 consecutive patients with various vitreoretinal disorders. The IOP was measured before surgery, at the end of surgery, and at 5 hours and 1 day after surgery using Tono-Pen XL. The IOP at the end of surgery was adjusted to 15.0 ± 2.0 mm Hg.
Intraocular pressure elevation (>25 mm Hg) was found in 55 (24.1%) and 52 (22.8%) patients at 5 hours and 1 day postoperatively, respectively. The IOP at 5 hours was significantly lower in patients with macular hole (MH) than in those with diabetic macular edema, proliferative diabetic retinopathy (PDR), proliferative vitreoretinopathy, or rhegmatogenous retinal detachment (RD). The IOP at 1 day was significantly higher in patients with PDR and RD than in those with MH and epiretinal membrane. Multiple regression analysis revealed that IOP at 5 hours postoperatively had a significant correlation with the number of laser photocoagulation, preoperative IOP, combined cataract surgery, and 20-gauge vitrectomy. The IOP at 1 day postoperatively was significantly associated with these 4 parameters as well as the severity of postoperative vitreous hemorrhage and use of expanding gas tamponade.
Intraocular pressure elevation was found in approximately one-quarter of cases within 1 day following vitrectomy. The risk factors for IOP elevation included number of laser photocoagulation, combined cataract surgery, severity of postoperative vitreous hemorrhage, and use of expanding gas tamponade.
确定各种玻璃体视网膜疾病行玻璃体切除术后即刻眼压升高的发生率及危险因素。
对228例连续的各种玻璃体视网膜疾病患者进行前瞻性研究。术前、手术结束时、术后5小时及1天使用Tono-Pen XL测量眼压。将手术结束时的眼压调整至15.0±2.0 mmHg。
术后5小时和1天分别有55例(24.1%)和52例(22.8%)患者出现眼压升高(>25 mmHg)。黄斑裂孔(MH)患者术后5小时的眼压显著低于糖尿病性黄斑水肿、增殖性糖尿病视网膜病变(PDR)、增殖性玻璃体视网膜病变或孔源性视网膜脱离(RD)患者。PDR和RD患者术后1天的眼压显著高于MH和视网膜前膜患者。多元回归分析显示,术后5小时的眼压与激光光凝次数、术前眼压、联合白内障手术及20G玻璃体切除术显著相关。术后1天的眼压与上述4个参数以及术后玻璃体出血的严重程度和使用膨胀性气体填塞显著相关。
玻璃体切除术后1天内约四分之一的病例出现眼压升高。眼压升高的危险因素包括激光光凝次数、联合白内障手术、术后玻璃体出血的严重程度和使用膨胀性气体填塞。