Barone Michele, Viggiani Maria Teresa, Amoruso Annabianca, Licinio Raffaele, Iannone Andrea, Montenegro Lucia, Scavo Maria Principia, Addante Irene, Di Leo Alfredo
Gastroenterology Unit, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy
Gastroenterology Unit, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
JPEN J Parenter Enteral Nutr. 2014 Nov;38(8):991-5. doi: 10.1177/0148607113498422. Epub 2013 Aug 9.
No data about the influence of age and underlying diseases on home enteral nutrition (HEN)-related complications are reported in the literature. Herein, we retrospectively investigated this issue by analyzing HEN-related complications in a cohort of consecutive patients grouped according to the underlying disease and age.
We reviewed the medical records of 101 patients referring to our team in 2007-2010 to obtain patients' demographic data, age, nutrition status, duration of HEN treatment, and type of HEN-related complications. They were divided in cancer and neurologic patients and subgrouped on the basis of their age. HEN-related complications were expressed as complication rates.
Patients with neurological diseases suffered a significantly higher number of complications as compared with cancer patients (P = .04). Age did not significantly influence complication rates. The mechanical complications were the most frequent. The majority of HEN-related complications were resolved at home.
Our data strongly suggest that HEN-related complications are influenced by underlying diseases and not by age. In neurologic patients, dementia, loss of autonomy, and the different therapies administered by PEG probably play an important role in increasing the number of HEN-related complications as compared with cancer patients. The most frequent complications can be managed at home, reducing the costs of hospitalizations and discomfort for the patient.
文献中未报道年龄和基础疾病对家庭肠内营养（HEN）相关并发症的影响。在此，我们通过分析一组根据基础疾病和年龄分组的连续患者的HEN相关并发症，对这一问题进行了回顾性研究。
我们回顾了2007年至2010年转诊至我们团队的101例患者的病历，以获取患者的人口统计学数据、年龄、营养状况、HEN治疗持续时间以及HEN相关并发症的类型。他们被分为癌症患者和神经疾病患者，并根据年龄进行亚组划分。HEN相关并发症以并发症发生率表示。
与癌症患者相比，神经疾病患者的并发症数量显著更高（P = 0.04）。年龄对并发症发生率没有显著影响。机械性并发症最为常见。大多数HEN相关并发症在家庭中得到解决。
我们的数据强烈表明，HEN相关并发症受基础疾病影响而非年龄。与癌症患者相比，在神经疾病患者中，痴呆、自主能力丧失以及经皮内镜下胃造口术（PEG）实施的不同治疗可能在增加HEN相关并发症数量方面起重要作用。大多数常见并发症可在家庭中处理，从而降低住院成本并减轻患者不适。
