Kaynar K, Songul Tat T, Ulusoy S, Cansiz M, Ozkan G, Gul S, Bektas O
Department of Nephrology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Hippokratia. 2012 Jul;16(3):236-40.
This study was performed to investigate nutritional parameters of hemodialysis patients by using anthropometric and biochemical measurements.
Data from the last 6 months of 22 adult hemodialysis patients with a mean age of 61 ± 14 years were analyzed retrospectively. Dialysis vintage, normalized protein catabolic rate (nPCR), serum biochemical parameters, mid arm muscle circumference (MAMC) were determined as mean and standard deviation. Correlations between the variables were computed by coefficient p of Pearson.
We found significant positive correlations: age of patients versus C-reactive protein, MAMC versus LDL-Cholesterol, MAMC versus body mass index, albumin versus hemoglobin. There were also significant negative correlations: age versus serum creatinine, age versus albumin, age versus intact parathyroid hormone (iPTH), dialysis vintage versus MAMC.
In conclusion, age seem to be negatively associated with iPTH and albumin. As dialysis vintage increases, muscle mass seems to decrease.
本研究旨在通过人体测量和生化检测来调查血液透析患者的营养参数。
回顾性分析22例平均年龄为61±14岁的成年血液透析患者过去6个月的数据。确定透析龄、标准化蛋白分解代谢率(nPCR)、血清生化参数、上臂中部肌肉周长(MAMC)的平均值和标准差。变量之间的相关性通过Pearson系数p计算。
我们发现显著的正相关:患者年龄与C反应蛋白、MAMC与低密度脂蛋白胆固醇、MAMC与体重指数、白蛋白与血红蛋白。也有显著的负相关:年龄与血清肌酐、年龄与白蛋白、年龄与完整甲状旁腺激素(iPTH)、透析龄与MAMC。
总之,年龄似乎与iPTH和白蛋白呈负相关。随着透析龄增加,肌肉量似乎减少。