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本文引用的文献

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Clinical report—Guidelines for the determination of brain death in infants and children: an update of the 1987 task force recommendations.临床报告——婴儿和儿童脑死亡判定指南:1987 年工作组建议的更新。
Pediatrics. 2011 Sep;128(3):e720-40. doi: 10.1542/peds.2011-1511. Epub 2011 Aug 28.
2
Diagnosis of brain death.脑死亡的诊断
Neurol Int. 2010 Jun 21;2(1):e2. doi: 10.4081/ni.2010.e2.
3
Brain death criteria. The neurological determination of death.脑死亡标准。死亡的神经学判定。
Neurosciences (Riyadh). 2008 Oct;13(4):350-5.
4
Reversal to whole-brain death criteria after 15-year experience with brain stem death criteria in Poland.
Transplant Proc. 2009 Oct;41(8):2959-60. doi: 10.1016/j.transproceed.2009.07.079.
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Variability in pediatric brain death determination and documentation in southern California.南加州儿科脑死亡判定与记录的差异
Pediatrics. 2008 May;121(5):988-93. doi: 10.1542/peds.2007-1871.
6
Brain death in infants and children.
Crit Care Nurse. 2006 Apr;26(2):117-24, 126-8.
7
Determination of brain death in children--a medicial center experience.儿童脑死亡的判定——某医学中心的经验
Acta Paediatr Taiwan. 2005 May-Jun;46(3):132-7.
8
The first organ transplant from a brain-dead donor.首例来自脑死亡供体的器官移植。
Neurology. 2005 Jun 14;64(11):1938-42. doi: 10.1212/01.WNL.0000163515.09793.CB.
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Determination of death.
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新生儿脑死亡诊断可行吗?

Is brain death diagnosis in newborns feasible?

作者信息

Chatziioannidis I, Chouchou P, Nikolaidis N

机构信息

Neonatal Intensive Care Unit A.U.T, GPN "Papageorgiou", Thessaloniki.

出版信息

Hippokratia. 2012 Oct;16(4):308-11.

PMID:23935308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3738603/
Abstract

Brain death as the irreversible and permanent loss of cerebral and brainstem function, is relatively uncommon among newborns who need life support. It is considered the result of an acute and irreversible central nervous system insult. Asphyxia, severe intracranial hemorrhage and infection are the most common causes of brain death in children. BD diagnosis is usually based on clinical criteria. Because of major differences of brain function in this age group, brain death should be established with extreme caution. Comparative to adults' longer observational periods (at least 24 hours apart) and specific neurodiagnostic tests, by at least two expert physicians, are needed to ascertain an irreversible loss of brain function. The objective of this article is to present current guidelines for BD determination in newborns and to refer their application in Greece.

摘要

脑死亡是指大脑和脑干功能不可逆转的永久性丧失,在需要生命支持的新生儿中相对少见。它被认为是急性不可逆中枢神经系统损伤的结果。窒息、严重颅内出血和感染是儿童脑死亡最常见的原因。脑死亡诊断通常基于临床标准。由于该年龄组脑功能存在重大差异,确定脑死亡应极其谨慎。与成人较长的观察期(至少间隔24小时)相比,确定新生儿脑功能不可逆转的丧失需要至少两名专家医生进行特定的神经诊断测试。本文的目的是介绍新生儿脑死亡判定的现行指南,并提及这些指南在希腊的应用情况。