Bonde J P
Department of Occupational Medicine, Hospital of Aalborg, Denmark.
Br J Ind Med. 1990 Aug;47(8):515-8. doi: 10.1136/oem.47.8.515.
In a cross sectional field study concerning the male reproductive system in metalworkers, the major findings were a moderate deterioration of semen quality in mild steel welders and less reliable changes in semen quality in low exposed stainless steel welders. In the present study, a longitudinal design was adopted to deal with methodological drawbacks inherent in the cross sectional approach. The study relies on the assumption that the effect of welding is causal and reversible. The semen quality of 19 mild steel welders, 18 stainless steel welders and 16 non-welding metal-workers, was examined before and three, five, and eight weeks after a three week break in exposure (summer vacation). No consistent improvement in any semen parameter in the follow up period relative to the prevacation period was found in either mild steel or stainless steel welders. The results indicate either a non-causal nature of reported associations between welding exposure and poor semen quality, or that the effect of welding is non-reversible within the rather short non-exposure period.
在一项关于金属工人男性生殖系统的横断面现场研究中，主要发现是低碳钢焊工的精液质量有中度恶化，而低暴露不锈钢焊工的精液质量变化不太可靠。在本研究中，采用纵向设计来处理横断面方法固有的方法学缺陷。该研究基于这样的假设，即焊接的影响是因果性的且是可逆的。对19名低碳钢焊工、18名不锈钢焊工和16名非焊接金属工人在暴露中断（暑假）三周前以及中断后三周、五周和八周时的精液质量进行了检查。在低碳钢或不锈钢焊工中，随访期间相对于假期前任何精液参数均未发现一致的改善。结果表明，要么焊接暴露与精液质量差之间所报告关联的性质并非因果关系，要么焊接的影响在相当短的非暴露期内是不可逆的。
