Jelnes J E, Knudsen L E
Department of Biology and Toxicology, Danish National Institute of Occupational Health, Copenhagen.
Reprod Toxicol. 1988;2(3-4):213-5. doi: 10.1016/0890-6238(88)90025-1.
Questionnaire studies of patients from fertility clinics suggest that welders may have an increased risk of reduced semen quality. In this study, welders and nonwelders from the same plants were asked to provide blood, urine, and semen samples. Urine was analyzed for chromium and nickel, and for mutagenic activity and metal concentration; blood for metal concentrations, immunoglobulin G, total protein, and measures of genotoxicity in lymphocytes; and semen was evaluated by standard semen analysis. Results of the semen evaluation, presented here, showed no difference in semen quality between welders and nonwelders. Because the metal dust exposure of nonwelders in the plant may be higher than that in the general population, welders were also compared to referents not working in the metal industry. Again, no decrease in semen quality associated with welding was demonstrated.
对来自生育诊所患者的问卷调查研究表明，焊工精液质量下降的风险可能会增加。在本研究中，来自同一家工厂的焊工和非焊工被要求提供血液、尿液和精液样本。对尿液进行铬和镍分析，以及诱变活性和金属浓度分析；对血液进行金属浓度、免疫球蛋白G、总蛋白和淋巴细胞遗传毒性检测；精液则通过标准精液分析进行评估。此处呈现的精液评估结果显示，焊工和非焊工的精液质量没有差异。由于工厂中非焊工的金属粉尘暴露可能高于一般人群，因此还将焊工与不在金属行业工作的对照人群进行了比较。同样，未证明焊接会导致精液质量下降。
