Kandalgaonkar Shilpa, Tupsakhare Suyog, Patil Ashok, Agrawal Gaurav, Gabhane Mahesh, Sonune Shrikant
Department Oral Pathology & Microbiology, SMBT Dental College & Hospital, Sangamner, Maharashtra 422608, India.
Case Rep Dent. 2013;2013:812323. doi: 10.1155/2013/812323. Epub 2013 Jul 10.
Solitary angiokeratoma of oral mucosa is rare entity. The term Angiokeratoma is used to refer to several lesions, whose common denominator is the presence of dilated blood vessels in association with epidermal hyperplasia. Mucosal involvement, including oral cavity is occasionally found either as a component of the systemic variety, cutaneous involvement or isolated oral involvement. Clinically, the lesion is irregular, whitish to dark brown in color, with female predominance. The etiological factors include injury, trauma, or chronic irritation to the wall of a papillary dermis. Histologically, it is characterized by hyperkeratosis, acanthosis, and dilated vascular spaces with or without organizing thrombi in papillary dermis. The vascular spaces are partly or completely enclosed by elongated ret-ridges. Along with this reporting a case of solitary angiokeratoma affecting tongue in a 38-year-old male patient, along with the literature review is presented.
口腔黏膜孤立性血管角化瘤是一种罕见的病变。血管角化瘤这一术语用于指代几种病变，其共同特征是存在扩张的血管并伴有表皮增生。黏膜受累，包括口腔受累，偶尔可作为系统性病变的一部分、皮肤受累或孤立的口腔受累情况被发现。临床上，病变不规则，颜色从白色到深褐色，女性多见。病因包括损伤、创伤或对乳头真皮壁的慢性刺激。组织学上，其特征为角化过度、棘层肥厚以及乳头真皮内扩张的血管腔，血管腔内可有或无机化血栓。血管腔部分或完全被拉长的表皮嵴所包绕。本文报告了一例38岁男性患者舌部的孤立性血管角化瘤病例，并进行了文献复习。
