Kirby R X, Mitchell D I, Williams N P, Cornwall D A, Cawich S O
Department of Surgery, Radiology, Anaesthesia and Intensive Care, University of the West Indies, Mona, Kingston 7, Jamaica.
Case Rep Surg. 2013;2013:198502. doi: 10.1155/2013/198502. Epub 2013 Jul 1.
Introduction. Whilst most consequences of diabetes mellitus are well recognized, breast-related complications remain obscure. The term diabetic mastopathy (DMP) attempts to describe the breast-related consequences of diabetes. Methods. We report the clinicopathologic findings in a patient with DMP and review the literature on this uncommon entity. Results. A 33-year-old woman with type 1 diabetes had excision biopsy of a 2 cm breast lump. Histopathologic evaluation revealed classic features of DMP: parenchymal fibrosis; keloid-like hyalinization of interlobular stroma; adipose tissue entrapment; lobular compression; dense chronic inflammatory cell infiltration; and lymphoid follicle formation. Conclusion. Clinicians should be aware of DMP as a differential for breast disease in women with uncontrolled diabetes.
引言。虽然糖尿病的大多数后果已广为人知，但与乳腺相关的并发症仍不清楚。糖尿病性乳腺病（DMP）这一术语试图描述糖尿病与乳腺相关的后果。方法。我们报告了1例DMP患者的临床病理结果，并复习了关于这一罕见实体的文献。结果。一名33岁的1型糖尿病女性对一个2厘米的乳腺肿块进行了切除活检。组织病理学评估显示DMP的典型特征：实质纤维化；小叶间质的瘢痕疙瘩样玻璃样变；脂肪组织包埋；小叶受压；密集的慢性炎症细胞浸润；以及淋巴滤泡形成。结论。临床医生应意识到DMP可作为糖尿病控制不佳女性乳腺疾病的鉴别诊断。
