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足月儿经皮胆红素测量的准确性。

Accuracy of transcutaneous bilirubin measurement in term newborns.

作者信息

Kosarat Shanika, Khuwuthyakorn Varangthip

机构信息

Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

出版信息

J Med Assoc Thai. 2013 Feb;96(2):172-7.

Abstract

OBJECTIVE

  1. To evaluate the accuracy of transcutaneous bilirubin (TcB) compared with serum bilirubin (TsB) in full-term infants, 2) To compare the accuracy of TcB reading from two, three, and four measurements and, 3) To compare the accuracy of TcB measured at the forehead and sternum.

MATERIAL AND METHOD

Full-term infants who were diagnosed neonatal jaundice and underwent blood tests for TsB were eligible for enrollment. Infants who were born at gestational age less than 37 weeks, unstable, previously received phototherapy, or exchange transfusion were excluded. TcB was measured at forehead and sternum two, three, and four times at each site. TcB measurements were done within 30 minutes before or after blood sampling for TsB.

RESULTS

The authors obtained 294 paired TcB-TsB from 257 full-term infants. TsB ranged from 1.60 to 21.18 mg/dL (mean 11.03, SD 2.73). The correlation coefficients between TcB at forehead and TsB were significant for two, three, and four measurements (r = 0.812, 0.800, and 0.800 respectively). TcB measured at sternum also had significant correlation with TsB (r = 0.829, 0.844, and 0.823 for two, three, and four measurements). TcB tended to underestimate TsB. Measurements at the sternum seemed to have better correlation with TsB than at the forehead.

CONCLUSION

TcB has good correlation coefficient to TsB. Two measurements have enough accuracy to estimate TsB level and measurement at the sternum gives better correlation with TsB than at forehead.

摘要

目的

1)评估足月儿经皮胆红素(TcB)与血清胆红素(TsB)相比的准确性;2)比较两次、三次和四次测量的TcB读数的准确性;3)比较在前额和胸骨处测量的TcB的准确性。

材料与方法

被诊断为新生儿黄疸并接受TsB血液检测的足月儿符合入组条件。排除孕周小于37周、病情不稳定、先前接受过光疗或换血治疗的婴儿。在每个部位的前额和胸骨处分别进行两次、三次和四次TcB测量。TcB测量在采集TsB血样前或后30分钟内完成。

结果

作者从257名足月儿中获得了294对TcB-TsB数据。TsB范围为1.60至21.18mg/dL(平均11.03,标准差2.73)。前额处的TcB与TsB之间的相关系数在两次、三次和四次测量时均具有显著性(分别为r = 0.812, 0.800和0.800)。胸骨处测量的TcB与TsB也具有显著相关性(两次、三次和四次测量时分别为r = 0.829, 0.844和0.823)。TcB往往会低估TsB。胸骨处的测量与TsB的相关性似乎比前额处更好。

结论

TcB与TsB具有良好的相关系数。两次测量就有足够的准确性来估计TsB水平,并且胸骨处的测量与TsB的相关性比前额处更好。

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