Srisuwan Patsri
Outpatient Department, Phramongkutklao Hospital, Bangkok, Thailand.
J Med Assoc Thai. 2013 Feb;96(2):251-8.
Dementia will inevitably increase in the aging world. Moreover there is no cure for dementia. Therefore, primary prevention is very important. There are several factors possibly and/or certainly influencing dementia risk including non-modifiable and modifiable risk factors. There are evidences that the risk of developing dementia may be reduced by modifiable risk factors. LIFESTYLE FACTORS: The strategies are to encourage regular physical and mental exercise in midlife and in late-life. Those include cognitive activity and higher education, mentally demanding occupations or participation in mentally challenging leisure activities, being more socially active, a diet that is low in saturated fat, a diet with lots of fruits and vegetables, smoking cessation, and prevention of head injury, with loss of consciousness. Chronic disease factors: The strategies are to prevent high blood pressure, especially at midlife, diabetes, high serum cholesterol, especially at midlife, and depression or high depressive symptoms.
It is important to develop a systematic public-health strategy and research specific to primary prevention of dementia in Thailand with the evidence-based medicine.
在人口老龄化的世界中，痴呆症将不可避免地增加。此外，痴呆症无法治愈。因此，一级预防非常重要。有几个因素可能和/或肯定会影响痴呆症风险，包括不可改变和可改变的风险因素。有证据表明，可改变的风险因素可能会降低患痴呆症的风险。
策略是鼓励中年和晚年进行定期的身体和精神锻炼。这些包括认知活动和高等教育、脑力要求高的职业或参与具有智力挑战性的休闲活动、社交更加活跃、饱和脂肪含量低的饮食、富含水果和蔬菜的饮食、戒烟以及预防头部受伤和意识丧失。
策略是预防高血压，尤其是在中年时，预防糖尿病、高血清胆固醇，尤其是在中年时，以及预防抑郁症或高抑郁症状。
利用循证医学制定针对泰国痴呆症一级预防的系统公共卫生策略和研究非常重要。
