Podoleanu Adrian Gh, Bradu Adrian
Applied Optics Group, School of Physical Sciences, University of Kent, CT2 7NH Canterbury, UK.
Opt Express. 2013 Aug 12;21(16):19324-38. doi: 10.1364/OE.21.019324.
Conventional spectral domain interferometry (SDI) methods suffer from the need of data linearization. When applied to optical coherence tomography (OCT), conventional SDI methods are limited in their 3D capability, as they cannot deliver direct en-face cuts. Here we introduce a novel SDI method, which eliminates these disadvantages. We denote this method as Master - Slave Interferometry (MSI), because a signal is acquired by a slave interferometer for an optical path difference (OPD) value determined by a master interferometer. The MSI method radically changes the main building block of an SDI sensor and of a spectral domain OCT set-up. The serially provided signal in conventional technology is replaced by multiple signals, a signal for each OPD point in the object investigated. This opens novel avenues in parallel sensing and in parallelization of signal processing in 3D-OCT, with applications in high- resolution medical imaging and microscopy investigation of biosamples. Eliminating the need of linearization leads to lower cost OCT systems and opens potential avenues in increasing the speed of production of en-face OCT images in comparison with conventional SDI.
传统的光谱域干涉测量（SDI）方法需要进行数据线性化处理。当应用于光学相干断层扫描（OCT）时，传统的SDI方法在三维成像能力方面存在局限性，因为它们无法提供直接的正面切割图像。在此，我们介绍一种新颖的SDI方法，该方法消除了这些缺点。我们将此方法称为主从干涉测量法（MSI），因为从干涉仪会针对由主干涉仪确定的光程差（OPD）值采集信号。MSI方法从根本上改变了SDI传感器和光谱域OCT装置的主要构建模块。传统技术中串行提供的信号被多个信号所取代，针对所研究物体中的每个OPD点都有一个信号。这为三维OCT中的并行传感和信号处理并行化开辟了新途径，可应用于高分辨率医学成像和生物样本的显微镜检查。无需进行线性化处理可降低OCT系统的成本，并且与传统SDI相比，为提高正面OCT图像的生成速度开辟了潜在途径。
