Abbott Lucy, Nteroli Gianni, Engelsholm Rasmus D, Montague Patrick Bowen, Podoleanu Adrian, Bradu Adrian
Applied Optics Group, School of Engineering, Mathematics and Physics, University of Kent, CT2 7NH, Canterbury, United Kingdom.
School of Electrical and Computer Engineering, Technical University of Crete, Greece.
Biomed Opt Express. 2025 Jun 23;16(7):2898-2913. doi: 10.1364/BOE.562672. eCollection 2025 Jul 1.
This paper comprehensively demonstrates the efficiency of balanced detection in a visible optical coherence tomography instrument employing a low-noise supercontinuum laser. By using an innovative technique for digitally aligning camera pixels, we achieved a noise floor reduction of up to 12.8 dB across the entire imaging depth range, particularly near the zero optical path difference between the interferometer arms. The instrument presented here operates at a central wavelength of 590 nm. It delivers high-resolution images with a sensitivity of up to 74 dB in a single spectrometer configuration and 92.8 dB in a balanced configuration. The enhancement in image contrast is exemplified through images of an optical phantom and images of a human thumb and nail.
本文全面展示了在采用低噪声超连续激光的可见光学相干断层扫描仪器中平衡检测的效率。通过使用一种创新技术对相机像素进行数字对齐,我们在整个成像深度范围内实现了高达12.8 dB的本底噪声降低,特别是在干涉仪臂之间光程差为零附近。这里介绍的仪器工作在中心波长590 nm。在单光谱仪配置下,它能提供高达74 dB灵敏度的高分辨率图像,在平衡配置下则为92.8 dB。通过光学仿体图像以及人类拇指和指甲的图像例证了图像对比度的增强。