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采用低噪声超连续谱激光器的平衡检测可见光学相干断层扫描技术

Balanced-detection visible optical coherence tomography with a low-noise supercontinuum laser.

作者信息

Abbott Lucy, Nteroli Gianni, Engelsholm Rasmus D, Montague Patrick Bowen, Podoleanu Adrian, Bradu Adrian

机构信息

Applied Optics Group, School of Engineering, Mathematics and Physics, University of Kent, CT2 7NH, Canterbury, United Kingdom.

School of Electrical and Computer Engineering, Technical University of Crete, Greece.

出版信息

Biomed Opt Express. 2025 Jun 23;16(7):2898-2913. doi: 10.1364/BOE.562672. eCollection 2025 Jul 1.

DOI:10.1364/BOE.562672
PMID:40677808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12265444/
Abstract

This paper comprehensively demonstrates the efficiency of balanced detection in a visible optical coherence tomography instrument employing a low-noise supercontinuum laser. By using an innovative technique for digitally aligning camera pixels, we achieved a noise floor reduction of up to 12.8 dB across the entire imaging depth range, particularly near the zero optical path difference between the interferometer arms. The instrument presented here operates at a central wavelength of 590 nm. It delivers high-resolution images with a sensitivity of up to 74 dB in a single spectrometer configuration and 92.8 dB in a balanced configuration. The enhancement in image contrast is exemplified through images of an optical phantom and images of a human thumb and nail.

摘要

本文全面展示了在采用低噪声超连续激光的可见光学相干断层扫描仪器中平衡检测的效率。通过使用一种创新技术对相机像素进行数字对齐，我们在整个成像深度范围内实现了高达12.8 dB的本底噪声降低，特别是在干涉仪臂之间光程差为零附近。这里介绍的仪器工作在中心波长590 nm。在单光谱仪配置下，它能提供高达74 dB灵敏度的高分辨率图像，在平衡配置下则为92.8 dB。通过光学仿体图像以及人类拇指和指甲的图像例证了图像对比度的增强。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/9d8dac85ab4d/boe-16-7-2898-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/6c5e5aef7837/boe-16-7-2898-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/d67d8221ce17/boe-16-7-2898-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/9ee395ddc7ca/boe-16-7-2898-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/38451483791d/boe-16-7-2898-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/f7261a2472ea/boe-16-7-2898-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/b4865b381c12/boe-16-7-2898-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/a6f41bf37945/boe-16-7-2898-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/f8adb9120ed0/boe-16-7-2898-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/14316f2a8950/boe-16-7-2898-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/05e6248660e2/boe-16-7-2898-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/9d8dac85ab4d/boe-16-7-2898-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/6c5e5aef7837/boe-16-7-2898-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/d67d8221ce17/boe-16-7-2898-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/9ee395ddc7ca/boe-16-7-2898-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/38451483791d/boe-16-7-2898-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/f7261a2472ea/boe-16-7-2898-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/b4865b381c12/boe-16-7-2898-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/a6f41bf37945/boe-16-7-2898-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/f8adb9120ed0/boe-16-7-2898-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/14316f2a8950/boe-16-7-2898-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/05e6248660e2/boe-16-7-2898-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/12265444/9d8dac85ab4d/boe-16-7-2898-g011.jpg

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本文引用的文献

1
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2
Visible-light optical coherence tomography platform for the characterization of the skin barrier.用于表征皮肤屏障的可见光光学相干断层扫描平台。
Biomed Opt Express. 2023 Jul 6;14(8):3914-3923. doi: 10.1364/BOE.494356. eCollection 2023 Aug 1.
3
Image-based cross-calibration method for multiple spectrometer-based OCT.基于图像的多光谱仪 OCT 交叉校准方法。
Opt Lett. 2022 Oct 1;47(19):5096-5099. doi: 10.1364/OL.468707.
4
Balanced detection spectral-domain optical coherence tomography with a single line-scan camera.基于单一线扫描相机的平衡探测谱域光学相干断层扫描技术。
Opt Express. 2022 Jan 17;30(2):2578-2584. doi: 10.1364/OE.446941.
5
High-Speed Balanced-Detection Visible-Light Optical Coherence Tomography in the Human Retina Using Subpixel Spectrometer Calibration.高速平衡探测可见光谱光学相干层析术在人视网膜中的应用：亚像元光谱仪校准。
IEEE Trans Med Imaging. 2022 Jul;41(7):1724-1734. doi: 10.1109/TMI.2022.3147497. Epub 2022 Jun 30.
6
Morphometry of Inner Plexiform Layer (IPL) Stratification in the Human Retina With Visible Light Optical Coherence Tomography.利用可见光光学相干断层扫描技术对人视网膜内网状层（IPL）分层进行形态测量
Front Cell Neurosci. 2021 Apr 29;15:655096. doi: 10.3389/fncel.2021.655096. eCollection 2021.
7
Incoherent excess noise spectrally encodes broadband light sources.非相干过量噪声对宽带光源进行光谱编码。
Light Sci Appl. 2020 Oct 6;9:172. doi: 10.1038/s41377-020-00404-6. eCollection 2020.
8
Retinal capillary oximetry with visible light optical coherence tomography.视网膜毛细血管血氧测定术结合可见 光光学相干断层扫描技术。
Proc Natl Acad Sci U S A. 2020 May 26;117(21):11658-11666. doi: 10.1073/pnas.1918546117. Epub 2020 May 12.
9
Supercontinuum noise reduction by fiber undertapering.通过光纤渐缩实现超连续谱降噪。
Opt Express. 2019 Apr 1;27(7):10320-10331. doi: 10.1364/OE.27.010320.
10
Recovering distance information in spectral domain interferometry.在光谱域干涉测量中恢复距离信息。
Sci Rep. 2018 Oct 18;8(1):15445. doi: 10.1038/s41598-018-33821-0.