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新西兰15岁以下儿童哮喘治疗及治疗效果的种族差异:基于全国数据库的分析

Ethnic disparities in asthma treatment and outcomes in children aged under 15 years in New Zealand: analysis of national databases.

作者信息

Gillies Todd D, Tomlin Andrew M, Dovey Susan M, Tilyard Murray W

机构信息

Best Practice Advocacy Centre, Dunedin, New Zealand.

出版信息

Prim Care Respir J. 2013 Sep;22(3):312-8. doi: 10.4104/pcrj.2013.00068.

Abstract

BACKGROUND

Mãori and Pacific children experience poorer outcomes relating to asthma management than other ethnicities.

AIMS

To measure recommended treatment and outcomes for asthma in all New Zealand children by age, sex, and ethnic group.

METHODS

Children aged <15 years dispensed >2 asthma medicines (N=80,514) were identified from the national pharmaceutical claims database. We measured the number of children dispensed oral steroids >2 times and hospital admissions with a primary diagnosis of asthma and compared asthma treatment steps and hospitalisation by age and ethnicity.

RESULTS

16.0% of children were dispensed asthma medicines, 9.2% were dispensed medicine >2 times, 3.6% of children were hospitalised at least once for asthma and 98.9% of admissions were acute. Mãori (OR 1.46, 95% CI 1.41 to 1.51) and Pacific children (OR 2.38, 95% CI 2.28 to 2.47) were more likely to remain on the lowest step of treatment. At all steps of treatment, Mãori and Pacific children had higher rates of oral steroid use. In all age groups, more Mãori children (5.1%, OR 1.88, 95% CI 1.73 to 2.04) and Pacific children (5.6%, OR 2.05, 95% CI 1.84 to 2.29) were hospitalised for asthma than children of other ethnicities (2.8%).

CONCLUSIONS

Mãori and Pacific children are less likely to have their treatment escalated to a higher step than other children. They are also more likely to use oral steroids to control asthma exacerbations and be admitted to hospital for severe asthma episodes. New Zealand databases can be used to monitor these outcomes.

摘要

背景

与其他种族相比,毛利族和太平洋岛民儿童在哮喘管理方面的结果较差。

目的

按年龄、性别和种族群体衡量所有新西兰儿童哮喘的推荐治疗方法和结果。

方法

从国家药品报销数据库中识别出年龄小于15岁且配发了超过2种哮喘药物的儿童(N = 80,514)。我们测量了配发口服类固醇超过2次的儿童数量以及以哮喘为主要诊断的住院人数,并按年龄和种族比较了哮喘治疗步骤和住院情况。

结果

16.0%的儿童配发了哮喘药物,9.2%的儿童配发药物超过2次,3.6%的儿童因哮喘至少住院一次,98.9%的住院是急性的。毛利族儿童(比值比1.46,95%置信区间1.41至1.51)和太平洋岛民儿童(比值比2.38,95%置信区间2.28至2.47)更有可能停留在最低治疗步骤。在治疗的各个步骤中,毛利族和太平洋岛民儿童口服类固醇的使用率更高。在所有年龄组中,因哮喘住院的毛利族儿童(5.1%,比值比1.88,95%置信区间1.73至2.04)和太平洋岛民儿童(5.6%,比值比2.05,95%置信区间1.84至2.29)比其他种族儿童(2.8%)更多。

结论

与其他儿童相比,毛利族和太平洋岛民儿童的治疗升级到更高步骤的可能性较小。他们也更有可能使用口服类固醇来控制哮喘发作,并因严重哮喘发作入院。新西兰的数据库可用于监测这些结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0023/6442824/c7fb6f35fe07/pcrj201368-f1.jpg

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