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模拟室内低温对哮喘儿童肺功能的影响。

Modelling the effects of low indoor temperatures on the lung function of children with asthma.

机构信息

He Kainga Oranga/Housing and Health Research Programme, Department of Public Health, University of Otago, , Wellington, New Zealand.

出版信息

J Epidemiol Community Health. 2013 Nov 1;67(11):918-25. doi: 10.1136/jech-2013-202632. Epub 2013 Aug 12.

DOI:10.1136/jech-2013-202632
PMID:23940250
Abstract

INTRODUCTION

While many epidemiological studies have shown that low outdoor temperatures are associated with increased rates of hospitalisation and mortality (especially for respiratory or cardiovascular disease), very few studies have looked at the association between indoor temperatures and health. Such studies are clearly warranted, as people have greater exposure to the indoor environment than the outdoor environment.

OBJECTIVES

To examine the relationship between various metrics of indoor temperature and lung function in children with asthma. Our specific research questions were: (1) In which room of the home is temperature most strongly associated with lung function? (2) Which exposure metric best describes the relationship between indoor temperature and lung function? (3) Over what lag/time period does indoor air temperature affect lung function most strongly?

METHODS

The Heating Housing and Health Study was a randomised controlled trial that investigated the effect of installing heaters in the homes of children with asthma. This study collected measurements of lung function (daily) and indoor temperature (hourly). Lung function and indoor temperature were measured for 309 children over 12 049 child-days. Statistical models were fitted to identify the best measures and metrics.

RESULTS

The strongest association with lung function was found for the severity of exposure to low bedroom temperatures averaged over the preceding periods of 0-7 to 0-12 days. A 1°C increase in temperature was associated with an average increase of 0.010, 0.008, 10.06, 12.06, in our four measures of lung function (peak expiratory flow rate (PEFR) morning, PEFR evening, forced expiratory volume in 1 s (FEV1) morning and FEV1 evening).

CONCLUSIONS

Indoor temperatures have a small, but significant, association with short-term variations in the lung function of children with asthma.

摘要

简介

尽管许多流行病学研究表明,较低的室外温度与住院率和死亡率(尤其是呼吸道或心血管疾病)的增加有关,但很少有研究关注室内温度与健康之间的关系。由于人们在室内环境中的暴露程度大于在室外环境中的暴露程度,因此此类研究显然是有必要的。

目的

研究室内温度的各种指标与哮喘儿童肺功能之间的关系。我们的具体研究问题是:(1)家中哪个房间的温度与肺功能最相关?(2)哪种暴露指标最能描述室内温度与肺功能之间的关系?(3)室内空气温度在多长的滞后/时间周期内对肺功能的影响最大?

方法

供暖住房与健康研究是一项随机对照试验,研究了在哮喘儿童家中安装加热器对其的影响。该研究收集了肺功能(每日)和室内温度(每小时)的测量数据。在 12049 个儿童日中,对 309 名儿童进行了肺功能和室内温度的测量。统计模型被用来确定最佳的测量指标和指标。

结果

与肺功能的最强关联是在前 0-7 至 0-12 天的时间段内发现的,即卧室温度的严重暴露程度。温度升高 1°C,与四个肺功能指标(清晨呼气峰流速(PEFR)、傍晚 PEFR、清晨用力呼气量 1 秒(FEV1)和傍晚 FEV1)的平均增加量分别为 0.010、0.008、10.06、12.06 相关。

结论

室内温度与哮喘儿童肺功能的短期变化有很小但显著的关联。

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