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免疫功能正常患者由毛霉属冬孢子毛霉引起的皮下接合菌病。

Subcutaneous zygomycosis caused by Mucor hiemalis in an immunocompetent patient.

作者信息

Desai Ravi Piraji, Joseph Noyal Mariya, Ananthakrishnan Nilakantan, Ambujam Sreedevi

机构信息

Department of General Surgery, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India.

出版信息

Australas Med J. 2013 Jul 31;6(7):374-7. doi: 10.4066/AMJ.2013.1764. Print 2013.

Abstract

Zygomycosis is an opportunistic fungal infection with a high mortality rate. It is known to cause invasive disease in immunocompromised hosts but it may produce only cutaneous/ subcutaneous infections in immunocompetent hosts. Treatment is difficult due to its fulminant course and lack of effective anti-fungal drugs. Here, we report a rare case of subcutaneous zygomycosis caused by Mucor hiemalis in an immunocompetent patient without any debilitating illness. The patient was successfully treated by aggressive surgical debridement and anti-fungal therapy.

摘要

接合菌病是一种机会性真菌感染,死亡率很高。已知它会在免疫功能低下的宿主中引起侵袭性疾病,但在免疫功能正常的宿主中可能仅产生皮肤/皮下感染。由于其病程迅猛且缺乏有效的抗真菌药物,治疗很困难。在此,我们报告一例罕见的由毛霉引起的皮下接合菌病,患者为免疫功能正常且无任何虚弱疾病的个体。该患者通过积极的手术清创和抗真菌治疗成功治愈。

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