Desai Ravi Piraji, Joseph Noyal Mariya, Ananthakrishnan Nilakantan, Ambujam Sreedevi
Department of General Surgery, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India.
Australas Med J. 2013 Jul 31;6(7):374-7. doi: 10.4066/AMJ.2013.1764. Print 2013.
Zygomycosis is an opportunistic fungal infection with a high mortality rate. It is known to cause invasive disease in immunocompromised hosts but it may produce only cutaneous/ subcutaneous infections in immunocompetent hosts. Treatment is difficult due to its fulminant course and lack of effective anti-fungal drugs. Here, we report a rare case of subcutaneous zygomycosis caused by Mucor hiemalis in an immunocompetent patient without any debilitating illness. The patient was successfully treated by aggressive surgical debridement and anti-fungal therapy.
接合菌病是一种机会性真菌感染，死亡率很高。已知它会在免疫功能低下的宿主中引起侵袭性疾病，但在免疫功能正常的宿主中可能仅产生皮肤/皮下感染。由于其病程迅猛且缺乏有效的抗真菌药物，治疗很困难。在此，我们报告一例罕见的由毛霉引起的皮下接合菌病，患者为免疫功能正常且无任何虚弱疾病的个体。该患者通过积极的手术清创和抗真菌治疗成功治愈。
