Loganathan Senthil, Ajay Gowtham A E, Thyagarajan U, Gokul Raj D
Department of Orthopaedics, Sri Ramachandra University, India.
J Clin Orthop Trauma. 2018 Mar;9(Suppl 1):S10-S14. doi: 10.1016/j.jcot.2017.10.005. Epub 2017 Oct 16.
Zygomycosis is the third leading cause of invasive fungal infection after candidiasis and aspergillosis. Although zygomycosis mostly affects immunocompromised individuals trauma may potentiate infection in immunocompetent individuals. The mortality rate of Zygomycosis is around 50% due to angioinvasion. Here we report a series of 5 cases of angio invasive fungal infection in immunocompetent individuals who sustained trauma in urban areas, out of which only one patient survived following high above knee amputation.
接合菌病是仅次于念珠菌病和曲霉病的第三大侵袭性真菌感染病因。尽管接合菌病大多影响免疫功能低下的个体，但创伤可能会使免疫功能正常的个体更易感染。由于血管侵袭，接合菌病的死亡率约为50%。在此，我们报告了一系列5例发生在城市地区、遭受创伤的免疫功能正常个体的血管侵袭性真菌感染病例，其中仅1例患者在进行高位膝上截肢术后存活。
