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溴氰菊酯在泌乳奶牛中的排泄情况。

Excretion of deltamethrin in lactating dairy cows.

作者信息

Venant A, Belli P, Borrel S, Mallet J

机构信息

C.N.E.V.A. Laboratoire Central d'Hygiène Alimentaire, Paris, France.

出版信息

Food Addit Contam. 1990 Jul-Aug;7(4):535-43. doi: 10.1080/02652039009373916.

Abstract

A study was conducted to determine the metabolic fate of deltamethrin in lactating cows after a 'pour-on' application. Two cows were treated with 0.1 g deltamethrin and two with 1 g of the compound. Urine, faeces, milk and blood were collected over an 8-day period and analyzed for deltamethrin. This preliminary experiment has shown that it is necessary to undertake further experiment of longer duration (1 month). Deltamethrin was rapidly absorbed and slowly excreted. In milk, residues levels were very low: less than 1% of the treatment dose, and maximum levels were reached after 2 days (0.009 micrograms/ml for 0.1 g deltamethrin and 0.053 micrograms/ml for 1 g deltamethrin). For cows 1 and 2 (0.1 g deltamethrin), no residue level was detected at the detection limit (0.001 micrograms/ml) after 8 days. A total of 0.3-0.6% of excreted deltamethrin was present in urine, and no residue was found after 8 days. The major route for elimination was via faeces (about 95% of the total eliminated compound). Maxima were reached after 2 days and were still present after 8 days. Results shown in this study substantiate previously published work.

摘要

进行了一项研究,以确定在泌乳奶牛进行“浇泼式”施药后溴氰菊酯的代谢归宿。给两头奶牛施用0.1克溴氰菊酯,给另外两头奶牛施用1克该化合物。在8天时间内收集尿液、粪便、牛奶和血液,并分析其中的溴氰菊酯。这项初步实验表明有必要进行持续时间更长(1个月)的进一步实验。溴氰菊酯吸收迅速,排泄缓慢。在牛奶中,残留水平非常低:低于处理剂量的1%,且在2天后达到最高水平(0.1克溴氰菊酯为0.009微克/毫升,1克溴氰菊酯为0.053微克/毫升)。对于奶牛1和2(施用0.1克溴氰菊酯),8天后在检测限(0.001微克/毫升)未检测到残留水平。排泄的溴氰菊酯中共有0.3 - 0.6%存在于尿液中,8天后未发现残留。主要排泄途径是通过粪便(约占总排泄化合物的95%)。2天后达到最高值,8天后仍有残留。本研究所示结果证实了先前发表的研究成果。

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