Dedek W, Grahl R, Schwarz H, Ludwig P
Arch Exp Veterinarmed. 1978;32(6):951-5.
Rafoxanide, labelled by 131J, was applied orally in the formulation "Ursovermit" to 2 lactating cows, 5 mg/kg bodymass, resp. Residues and halflifes in blood, milk and meat and the excretion in urine are given, related to 131J in the chloroform extract. 3,5-diiodosalicyclic acid was found as metabolite in amounts of 1-2,5%, relative to rafoxanide, resp.
用131J标记的雷复尼特以“Ursovermit”制剂形式口服给予2头泌乳奶牛,剂量为5毫克/千克体重。给出了血液、牛奶和肉类中的残留量、半衰期以及尿液排泄情况,以氯仿提取物中的131J为参照。发现3,5 - 二碘水杨酸作为代谢产物,相对于雷复尼特分别为1 - 2.5%。