Starmer Heather M, Riley Lee H, Hillel Alexander T, Akst Lee M, Best Simon R A, Gourin Christine G
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Outpatient Center, 601 N. Caroline Street Suite 6260, Baltimore, MD, 21287, USA,
Dysphagia. 2014 Feb;29(1):68-77. doi: 10.1007/s00455-013-9482-9. Epub 2013 Aug 14.
Dysphonia and dysphagia are common complications of anterior cervical discectomy (ACD). We sought to determine the relationship between dysphagia and in-hospital mortality, complications, speech therapy/dysphagia training, length of hospitalization, and costs associated with ACD. Discharge data from the Nationwide Inpatient Sample for 1,649,871 patients who underwent ACD of fewer than four vertebrae for benign acquired disease between 2001 and 2010 were analyzed using cross-tabulations and multivariate regression modeling. Dysphagia was reported in 32,922 cases (2.0 %). Speech therapy/dysphagia training was reported in less than 0.1 % of all cases and in only 0.2 % of patients with dysphagia. Dysphagia was significantly associated with age ≥65 years (OR = 1.5 [95 % CI 1.4-1.7], P < 0.001), advanced comorbidity (OR = 2.3 [2.0-2.6], P < 0.001), revision surgery (OR = 2.7 [2.3-3.1], P < 0.001), disc prosthesis placement (OR = 1.5 [1.0-2.0], P = 0.029), and vocal cord paralysis (OR = 11.6 [8.3-16.1], P < 0.001). Dysphagia was a significant predictor of aspiration pneumonia (OR = 8.6 [6.7-10.9], P < 0.001), tracheostomy (OR = 2.3 [1.6-3.3], P < 0.001), gastrostomy (OR = 30.9 [25.3-37.8], P < 0.001), and speech therapy/dysphagia training (OR = 32.0 [15.4-66.4], P < 0.001). Aspiration pneumonia was significantly associated with in-hospital mortality (OR = 15.9 [11.0-23.1], P < 0.001). Dysphagia, vocal cord paralysis, and aspiration pneumonia were significant predictors of increased length of hospitalization and hospital-related costs, with aspiration pneumonia having the single largest impact on length of hospitalization and costs. Dysphagia is significantly associated with increased morbidity, length of hospitalization, and hospital-related costs in ACD patients. Despite the known risk of dysphagia in ACD patients and an established role for the speech-language pathologist in dysphagia management, speech-language pathology intervention appears underutilized in this population.
发音障碍和吞咽困难是颈椎前路椎间盘切除术(ACD)常见的并发症。我们试图确定吞咽困难与住院死亡率、并发症、言语治疗/吞咽困难训练、住院时间以及与ACD相关的费用之间的关系。使用交叉表和多变量回归模型分析了2001年至2010年间全国住院患者样本中1,649,871例因良性后天性疾病接受少于四个椎体ACD手术患者的出院数据。32,922例(2.0%)报告有吞咽困难。言语治疗/吞咽困难训练在所有病例中报告的比例不到0.1%,仅在0.2%有吞咽困难的患者中进行了报告。吞咽困难与年龄≥65岁(OR = 1.5 [95% CI 1.4 - 1.7],P < 0.001)、严重合并症(OR = 2.3 [2.0 - 2.6],P < 0.001)、翻修手术(OR = 2.7 [2.3 - 3.1],P < 0.001)、椎间盘假体置入(OR = 1.5 [1.0 - 2.0],P = 0.029)以及声带麻痹(OR = 11.6 [8.3 - 16.1],P < 0.001)显著相关。吞咽困难是吸入性肺炎(OR = 8.6 [6.7 - 10.9],P < 0.001)、气管切开术(OR = 2.3 [1.6 - 3.3],P < 0.001)、胃造口术(OR = 30.9 [25.3 - 37.8],P < 0.001)以及言语治疗/吞咽困难训练(OR = 32.0 [15.4 - 66.4],P < 0.001)的显著预测因素。吸入性肺炎与住院死亡率显著相关(OR = 15.9 [11.0 - 23.1],P < 0.001)。吞咽困难、声带麻痹和吸入性肺炎是住院时间延长和医院相关费用增加的显著预测因素,其中吸入性肺炎对住院时间和费用的影响最大。吞咽困难与ACD患者发病率增加、住院时间延长以及医院相关费用显著相关。尽管已知ACD患者存在吞咽困难风险,且言语病理学家在吞咽困难管理中具有既定作用,但言语病理学干预在该人群中似乎未得到充分利用