Department of Immunology, Faculty of Health Sciences, University of Pretoria, P.O. Box 2034, Pretoria, 0001, South Africa.
Stem Cell Rev Rep. 2013 Dec;9(6):752-63. doi: 10.1007/s12015-013-9463-2.
South Africa (SA) faces a large unmet need for bone marrow (BM) transplantation, which could be alleviated in part by establishing a public umbilical cord blood stem cell bank (UCB SCB). Umbilical cord blood is an increasingly utilised source of hematopoietic stem cells for BM transplantation in addition to BM or mobilized peripheral blood stem cells. Establishing a public UCB SCB would therefore be a positive step towards improving the quality of health care in SA by providing for an important unmet need. This study takes the form of an enquiry into the acceptability of establishing a public bank through an interview with and questionnaire completed by mothers-to-be in the antenatal clinic of a large public hospital in SA. Initial results are positive, with 85 % of the participants in favour of establishing a public UCB SCB in SA. This initial probe will serve as a model for a more comprehensive national enquiry into public support and acceptability in different clinics, hospitals and provinces in SA.
南非(SA)面临着大量未满足的骨髓(BM)移植需求,这在一定程度上可以通过建立公共脐带血干细胞库(UCB SCB)来缓解。除了骨髓或动员外周血干细胞外,脐带血是 BM 移植中造血干细胞的越来越多的来源。因此,建立公共 UCB SCB 将是朝着改善南非医疗保健质量迈出的积极一步,因为这满足了一项重要的未满足需求。这项研究通过对南非一家大型公立医院产前诊所的孕妇进行访谈和问卷调查,探讨了建立公共银行的可接受性。初步结果是积极的,85%的参与者赞成在南非建立公共 UCB SCB。这一初步调查将作为在南非不同诊所、医院和省份进行更全面的全国性公共支持和可接受性调查的模型。