从球子蕨根茎和叶基部中分离得到的两种新的C-甲基黄烷酮。

Two new C-methyl flavanones from the rhizomes and frond bases of Matteuccia struthiopteris.

作者信息

Zhang Dong, Li Shu-Bei, Yang Lan, Li Yu-Jie, Zhu Xiao-Xin, Kmoníčková Eva, Zídek Zdeněk, Fu Mei-Hong, Fang Jing

机构信息

a Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences , Beijing , 100700 , China.

出版信息

J Asian Nat Prod Res. 2013 Nov;15(11):1163-7. doi: 10.1080/10286020.2013.826204. Epub 2013 Aug 14.

DOI:10.1080/10286020.2013.826204

PMID:23944953

Abstract

Two new C-methyl flavanones, (2S)-5,7-dihydroxy-6,8-dimethyl-4'-methoxydihydroflavone-7-O-(6″-O-acetyl)-β-d-glucopyranoside (1) and (2S)-5,7-dihydroxy-6,8-dimethyldihydroflavone-7-O-(6″-O-acetyl)-β-d-glucopyranoside (2), together with five known compounds, demethoxymatteucinol-7-O-β-d-glucopyranoside (3), matteucinol-7-O-β-d-glucopyranoside (4), 5,7-dihydroxy-6-methyl-4'-methoxydihydroflavone (5), methoxymatteucin (6), and thunberginol C (7), were first isolated from the EtOH extract of the rhizomes and frond bases of Matteuccia struthiopteris. The structures were established by spectral analyses, mainly HR-ESI-MS and 1D and 2D NMR experiments (COSY, HSQC, and HMBC).

摘要

从球子蕨根茎和叶基部的乙醇提取物中首次分离得到两种新的C-甲基黄烷酮，即(2S)-5,7-二羟基-6,8-二甲基-4'-甲氧基二氢黄酮-7-O-(6″-O-乙酰基)-β-D-吡喃葡萄糖苷(1)和(2S)-5,7-二羟基-6,8-二甲基二氢黄酮-7-O-(6″-O-乙酰基)-β-D-吡喃葡萄糖苷(2)，以及5种已知化合物，去甲氧基马特乌西诺醇-7-O-β-D-吡喃葡萄糖苷(3)、马特乌西诺醇-7-O-β-D-吡喃葡萄糖苷(4)、5,7-二羟基-6-甲基-4'-甲氧基二氢黄酮(5)、甲氧基马特乌西因(6)和黑松素C(7)。通过光谱分析，主要是高分辨电喷雾电离质谱(HR-ESI-MS)以及一维和二维核磁共振实验(COSY、HSQC和HMBC)确定了它们的结构。