• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

利用遗传信息检验横断面数据中的因果关系。

Using genetic information to test causal relationships in cross-sectional data.

作者信息

Verhulst Brad, Estabrook Ryne

机构信息

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, USA.

出版信息

J Theor Polit. 2012 Jul;24(3):328-344. doi: 10.1177/0951629812439348.

DOI:10.1177/0951629812439348
PMID:23946557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3740451/
Abstract

Cross-sectional data from twins contain information that can be used to derive a test of causality between traits. This test of directionality is based upon the fact that genetic relationships between family members conform to an established structural pattern. In this paper we examine several common methods for empirically testing causality as well as several genetic models that we build on for the Direction of Causation (DoC) model. We then discuss the mathematical components of the DoC model and highlight limitations of the model and potential solutions to these limitations. We conclude by presenting an example from the personality and politics literature that has begun to explore the question whether or not personality traits cause people to hold specific political attitudes.

摘要

双胞胎的横断面数据包含可用于推导性状之间因果关系检验的信息。这种方向性检验基于家庭成员之间的遗传关系符合既定结构模式这一事实。在本文中,我们研究了几种用于实证检验因果关系的常用方法,以及我们为因果方向(DoC)模型所构建的几种遗传模型。然后,我们讨论了DoC模型的数学组成部分,并强调了该模型的局限性以及针对这些局限性的潜在解决方案。我们通过展示人格与政治文献中的一个例子来结束本文,该例子已开始探讨人格特质是否会导致人们持有特定政治态度这一问题。

相似文献

1
Using genetic information to test causal relationships in cross-sectional data.利用遗传信息检验横断面数据中的因果关系。
J Theor Polit. 2012 Jul;24(3):328-344. doi: 10.1177/0951629812439348.
2
Correlation not causation: the relationship between personality traits and political ideologies.相关性并不等于因果性:人格特质与政治意识形态之间的关系。
Am J Pol Sci. 2012;56(1):34-51. doi: 10.1111/j.1540-5907.2011.00568.x.
3
Political attitudes develop independently of personality traits.政治态度的形成独立于人格特质。
PLoS One. 2015 Mar 3;10(3):e0118106. doi: 10.1371/journal.pone.0118106. eCollection 2015.
4
New evidence on the link between genes, psychological traits, and political engagement.关于基因、心理特征与政治参与之间联系的新证据。
Politics Life Sci. 2019 May 1;38(1):1-13. doi: 10.1017/pls.2019.3.
5
Testing hypotheses about direction of causation using cross-sectional family data.使用横断面家庭数据检验关于因果关系方向的假设。
Behav Genet. 1993 Jan;23(1):29-50. doi: 10.1007/BF01067552.
6
Inferring the direction of causation in cross-sectional twin data: theoretical and empirical considerations.推断横断面双生子数据中的因果关系方向:理论与实证考量
Genet Epidemiol. 1994;11(6):483-502. doi: 10.1002/gepi.1370110606.
7
Biometrical genetics.生物统计学遗传学
Biol Psychol. 2002 Oct;61(1-2):33-51. doi: 10.1016/s0301-0511(02)00051-0.
8
Integrating classical and contemporary explanations of political participation.整合对政治参与的经典解释与当代解释。
Twin Res Hum Genet. 2012 Feb;15(1):42-51. doi: 10.1375/twin.15.1.42.
9
A Major Limitation of the Direction of Causation Model: Non-Shared Environmental Confounding.因果关系模型方向的一个主要局限:非共享环境混杂因素。
Twin Res Hum Genet. 2019 Feb;22(1):14-26. doi: 10.1017/thg.2018.67. Epub 2019 Jan 21.
10
Genetic and environmental variation in political orientation in adolescence and early adulthood: A Nuclear Twin Family analysis.青少年和成年早期政治取向的遗传和环境变异:核双生子家庭分析。
J Pers Soc Psychol. 2020 Apr;118(4):762-776. doi: 10.1037/pspp0000258. Epub 2019 Jul 1.

引用本文的文献

1
On the Detection of Population Heterogeneity in Causation Between Two Variables: Finite Mixture Modeling of Data Collected from Twin Pairs.关于两个变量因果关系中总体异质性的检测:从双胞胎对收集的数据的有限混合模型
Behav Genet. 2025 Jan;55(1):59-70. doi: 10.1007/s10519-024-10207-9. Epub 2024 Nov 26.
2
Exploring associations between ADHD symptoms and emotional problems from childhood to adulthood: shared aetiology or possible causal relationship?探索从童年到成年期注意力缺陷多动障碍症状与情绪问题之间的关联:共同病因还是可能的因果关系?
Psychol Med. 2024 Nov 18;54(15):1-12. doi: 10.1017/S0033291724002514.
3
Calculating Within-Pair Difference Scores in the Co-twin Control Design. Effects of Alternative Strategies.

本文引用的文献

1
OpenMx: An Open Source Extended Structural Equation Modeling Framework.OpenMx:一个开源的扩展结构方程建模框架。
Psychometrika. 2011 Apr 1;76(2):306-317. doi: 10.1007/s11336-010-9200-6.
2
Correlation not causation: the relationship between personality traits and political ideologies.相关性并不等于因果性:人格特质与政治意识形态之间的关系。
Am J Pol Sci. 2012;56(1):34-51. doi: 10.1111/j.1540-5907.2011.00568.x.
3
Modeling extended twin family data I: description of the Cascade model.扩展双胞胎家庭数据建模I:级联模型描述
在同卵双生子对照设计中计算对子内差异得分。替代策略的影响。
Behav Genet. 2024 Sep;54(5):426-435. doi: 10.1007/s10519-024-10196-9. Epub 2024 Aug 23.
4
On the detection of population heterogeneity in causation between two variables: Finite mixture modeling of data collected from twin pairs.关于两个变量之间因果关系中总体异质性的检测:对双胞胎对收集的数据进行有限混合建模。
Res Sq. 2024 Jul 13:rs.3.rs-4576809. doi: 10.21203/rs.3.rs-4576809/v1.
5
The relationship of school performance with self-control and grit is strongly genetic and weakly causal.学业成绩与自我控制和毅力之间的关系具有很强的遗传性,因果关系较弱。
NPJ Sci Learn. 2023 Dec 4;8(1):53. doi: 10.1038/s41539-023-00198-3.
6
Associations Between Traumatic Stress, Brain Volumes and Post-traumatic Stress Disorder Symptoms in Children: Data from the ABCD Study.创伤后应激、大脑体积与儿童创伤后应激障碍症状的相关性:来自 ABCD 研究的数据。
Behav Genet. 2022 Mar;52(2):75-91. doi: 10.1007/s10519-021-10092-6. Epub 2021 Dec 3.
7
Dietary Influence on Systolic and Diastolic Blood Pressure in the TwinsUK Cohort.饮食对 TwinsUK 队列收缩压和舒张压的影响。
Nutrients. 2020 Jul 17;12(7):2130. doi: 10.3390/nu12072130.
8
Unraveling the Relation Between Reading Comprehension and Print Exposure.揭示阅读理解与印刷品接触之间的关系。
Child Dev. 2020 Sep;91(5):1548-1562. doi: 10.1111/cdev.13339. Epub 2019 Nov 15.
9
Onset of regular cannabis use and adult sleep duration: Genetic variation and the implications of a predictive relationship.规律使用大麻与成人睡眠时间:遗传变异与预测关系的影响。
Drug Alcohol Depend. 2019 Nov 1;204:107517. doi: 10.1016/j.drugalcdep.2019.06.019. Epub 2019 Aug 30.
10
The analysis of causal relationships between blood lipid levels and BMD.血脂水平与 BMD 之间因果关系的分析。
PLoS One. 2019 Feb 22;14(2):e0212464. doi: 10.1371/journal.pone.0212464. eCollection 2019.
Twin Res Hum Genet. 2009 Feb;12(1):8-18. doi: 10.1375/twin.12.1.8.
4
Multivariate genetic analysis of sex limitation and G x E interaction.性别限制和基因与环境交互作用的多变量遗传分析
Twin Res Hum Genet. 2006 Aug;9(4):481-9. doi: 10.1375/183242706778024937.
5
Testing mediational models with longitudinal data: questions and tips in the use of structural equation modeling.使用纵向数据检验中介模型:结构方程模型应用中的问题与技巧
J Abnorm Psychol. 2003 Nov;112(4):558-77. doi: 10.1037/0021-843X.112.4.558.
6
Direction of causation modeling between cross-sectional measures of parenting and psychological distress in female twins.女性双胞胎中养育方式的横断面测量与心理困扰之间的因果关系建模方向
Behav Genet. 2003 Jul;33(4):383-96. doi: 10.1023/a:1025365325016.
7
Testing hypotheses about direction of causation using cross-sectional family data.使用横断面家庭数据检验关于因果关系方向的假设。
Behav Genet. 1993 Jan;23(1):29-50. doi: 10.1007/BF01067552.
8
Genes, environment, and personality.基因、环境与个性。
Science. 1994 Jun 17;264(5166):1700-1. doi: 10.1126/science.8209250.
9
Weighted least squares analysis of repeated categorical measurements with outcomes subject to nonresponse.对存在无应答结果的重复分类测量进行加权最小二乘法分析。
Biometrics. 1994 Mar;50(1):11-24.
10
Depression and parental bonding: cause, consequence, or genetic covariance?抑郁症与父母养育方式:原因、结果还是基因共变?
Genet Epidemiol. 1994;11(6):503-22. doi: 10.1002/gepi.1370110607.