Xenos Michalis, Karakitsos Dimitrios, Labropoulos Nicos, Tassiopoulos Apostolos, Bilfinger Thomas V, Bluestein Danny
a Department of Mathematics , University of Ioannina , Ioannina , Greece.
Comput Methods Biomech Biomed Engin. 2015;18(4):414-25. doi: 10.1080/10255842.2013.805210. Epub 2013 Aug 16.
A right-sided aorta is a rare malformation which may be associated with other various types of congenital heart disease. We utilised haemodynamic, echocardiographic measurements, computerised tomography and image reconstruction software packages that were integrated in a computational fluid dynamics model to determine blood flow patterns in patient-based aortas. In the left-sided aorta, a systolic clockwise rotational component was present, while helical flow was depicted in the aortic arch that was converted in the descending aorta as counter-rotating vortices with accompanying retrograde flow. The right-sided configuration has not altered the orientation of the three-dimensional vortex, but intensification of polymorphic flow patterns, alterations in wall shear stress distribution and development of a lateral pressure gradient at the area of an aneurysmal anomaly was observed. Moreover, increments of Reynolds, Womersley and Dean numbers were evident. These phenomena along with the formation of the aneurysm might influence cardiovascular risk in patients with right-sided aortas.
右位主动脉是一种罕见的畸形，可能与其他各种类型的先天性心脏病有关。我们利用血流动力学、超声心动图测量、计算机断层扫描和集成在计算流体动力学模型中的图像重建软件包，来确定基于患者的主动脉中的血流模式。在左位主动脉中，存在收缩期顺时针旋转成分，而在主动脉弓中呈现螺旋流，在降主动脉中转变为反向旋转的涡流并伴有逆向血流。右位结构并未改变三维涡流的方向，但观察到多形性血流模式增强、壁面剪应力分布改变以及在动脉瘤异常区域出现侧向压力梯度。此外，雷诺数、沃默斯利数和迪恩数明显增加。这些现象以及动脉瘤的形成可能会影响右位主动脉患者的心血管风险。
