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基于人群的性少数女性心血管疾病风险研究。

A population-based study of cardiovascular disease risk in sexual-minority women.

机构信息

Grant W. Farmer is with the Department of Epidemiology, Saint Louis University School of Public Health, St. Louis, MO. Jennifer M. Jabson and Deborah J. Bowen are with the Department of Community Health Sciences, Boston University School of Public Health, Boston, MA. Kathleen K. Bucholz is with the Department of Psychiatry, Washington University School of Medicine, St. Louis.

出版信息

Am J Public Health. 2013 Oct;103(10):1845-50. doi: 10.2105/AJPH.2013.301258. Epub 2013 Aug 15.

DOI:10.2105/AJPH.2013.301258
PMID:23948018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3780727/
Abstract

OBJECTIVES

We sought to determine if sexual-minority women were at greater risk for cardiovascular disease (CVD) than their heterosexual counterparts.

METHODS

We aggregated data from the 2001-2008 National Health and Nutrition Examination Surveys to examine differences in CVD risk between heterosexual and sexual-minority women by using the Framingham General CVD Risk Score to calculate a ratio of vascular and chronological age. We also examined differences in the prevalence of various CVD risk factors.

RESULTS

Sexual-minority women were more likely to be current or former smokers, to report a history of drug use, to report risky drinking, and to report a family history of CVD. On average, sexual-minority women were 13.9% (95% confidence interval [CI] = 8.5%, 19.3%) older in vascular terms than their chronological age, which was 5.7% (95% CI = 1.5%, 9.8%) greater than that of their heterosexual counterparts. Family history of CVD and history of drug use were unrelated to increased CVD risk, and this risk was not fully explained by either risky drinking or smoking.

CONCLUSIONS

Sexual-minority women are at increased risk for CVD compared with heterosexual women.

摘要

目的

我们试图确定与异性恋女性相比,性少数群体女性患心血管疾病 (CVD) 的风险是否更高。

方法

我们汇总了 2001-2008 年全国健康和营养调查的数据,使用弗雷明汉一般 CVD 风险评分来计算血管年龄与实际年龄的比值,以评估异性恋和性少数群体女性之间 CVD 风险的差异。我们还研究了各种 CVD 风险因素的患病率差异。

结果

性少数群体女性更有可能是当前或曾经的吸烟者,有药物使用史,有危险饮酒行为,并有 CVD 家族史。平均而言,性少数群体女性在血管年龄方面比实际年龄大 13.9%(95%置信区间 [CI] = 8.5%,19.3%),比异性恋女性大 5.7%(95% CI = 1.5%,9.8%)。CVD 家族史和药物使用史与 CVD 风险增加无关,且这种风险不能完全由危险饮酒或吸烟来解释。

结论

与异性恋女性相比,性少数群体女性患 CVD 的风险更高。

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