Cancer Prevention and Control Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111-2497, USA.
Cancer Cell. 2013 Aug 12;24(2):145-7. doi: 10.1016/j.ccr.2013.07.018.
Cytokines have recently emerged as important players in tumor promotion and progression. In this issue of Cancer Cell, Putoczki and colleagues report the importance of interleukin 11 in a variety of gastrointestinal malignances and lay down a framework for its potential inhibition in a variety of human cancers.
细胞因子最近成为肿瘤促进和进展的重要参与者。在本期《癌细胞》中,Putoczki 及其同事报告了白细胞介素 11 在多种胃肠道恶性肿瘤中的重要性,并为其在多种人类癌症中的潜在抑制作用奠定了框架。