Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia; Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Ophthalmology. 2014 Jan;121(1):377-380. doi: 10.1016/j.ophtha.2013.06.044. Epub 2013 Aug 12.
To review the risk factors, management, and visual outcomes of pediatric chemical eye injuries in a tertiary care hospital in North India.
Retrospective hospital-based study.
Patients aged <16 years with ocular chemical burns.
Case records of patients with ocular chemical injury who presented to the Dr. Rajendra Prasad Centre for Ophthalmic Sciences were reviewed over a 5-year period.
Demographic profile, nature of chemical injury, complications, and visual outcomes after chemical injury.
A total of 134 pediatric patients with a history of ocular chemical burns were seen between March 2006 and March 2011. The mean age of patients at the time of injury was 8.95±4.89 years (range, 1.2-15.5 years); 63.4% were male. Sixty-nine patients (51.4%) belonged to the preschool (0-5 years) age group. Bilateral chemical injuries were seen in 24 patients (17.9%). Lime ("chuna") was the most commonly involved chemical (88, 65.6%) followed by toilet cleaner (20, 14.9%). The mean time between injury and presentation was 68.3 days (range, 1-365 days). Severe (grade 3 and 4) ocular chemical injury was seen in 94 patients (70.1%). Surgical intervention was performed in 114 eyes (85%) in the form of amniotic membrane grafting (n = 78), symblepharon release (n = 56), limbal stem cell transplantation (n = 26), and lamellar keratoplasty (n = 14). The average number of surgeries conducted per patient was 2.3 (range, 1-4). Median visual acuity at final follow-up (mean, 537±354 days) was 3/60.
Chemical injuries in pediatric patients are more commonly encountered in the preschool age group and are associated with severe visual loss. Alkali injury from bursting of chuna packets was the most common mode of injury in pediatric patients in our study.
回顾印度北部一家三级护理医院儿科化学性眼外伤的危险因素、处理方法和视力结果。
回顾性医院病例研究。
患有眼部化学灼伤的年龄＜16 岁的患者。
对 2006 年 3 月至 2011 年 3 月在 Dr. Rajendra Prasad 眼科中心就诊的眼部化学性损伤患者的病历进行了回顾。
人口统计学特征、化学性损伤性质、并发症和化学性损伤后的视力结果。
2006 年 3 月至 2011 年 3 月间，共有 134 名患有眼部化学性烧伤的儿科患者就诊。损伤时患者的平均年龄为 8.95±4.89 岁（范围 1.2-15.5 岁）；63.4%为男性。69 例（51.4%）患者属于学龄前（0-5 岁）年龄组。24 例（17.9%）患者为双眼化学性损伤。石灰（“chuna”）是最常见的化学物质（88 例，占 65.6%），其次是厕所清洁剂（20 例，占 14.9%）。损伤至就诊的平均时间为 68.3 天（范围 1-365 天）。94 例（70.1%）患者为重度（3 级和 4 级）眼部化学性损伤。114 只眼（85%）接受了手术干预，形式为羊膜移植（n=78）、睑球粘连松解术（n=56）、角膜缘干细胞移植（n=26）和板层角膜移植（n=14）。每位患者平均接受手术治疗 2.3 次（范围 1-4 次）。末次随访时的平均视力（中位数，537±354 天）为 3/60。
儿科患者的化学性损伤更常见于学龄前，且与严重视力丧失相关。在本研究中，来自石灰包爆裂的碱性损伤是儿科患者最常见的损伤模式。
