Department of Psychological Sciences, University of Missouri-Columbia, Columbia, Missouri 65211, USA
J Stud Alcohol Drugs. 2013 Sep;74(5):703-13. doi: 10.15288/jsad.2013.74.703.
Previous research has established a connection between early age at drinking initiation and greater alcohol involvement in adulthood, but it has not yet been established whether this is a causal effect. The current study used a multilevel discordant twin design to examine individual and contextual effects, and an interaction between these effects, of the age at drinking initiation on the frequency and quantity of drinking in adulthood.
Participants were 4,194 same-sex twins (2,264 monozygotic, 1,924 dizygotic; 2,270 women; Mage = 29.9 years) from the Australian Twin Registry who completed a telephone interview that included assessments of the age at alcohol use initiation and past-year frequency and quantity of alcohol use. Multilevel models were estimated using data from the full sample and using data from only monozygotic twins. Individual (within-twin-pair comparison) and family contextual (between-twin-pair comparison) effects were estimated.
The age at first drink was related to the past-year frequency (r = -.16) and quantity of drinking (r = -.12) in young adulthood. Individual (causal) and family context effects of age at drinking onset predicted later adult drinking frequency and quantity. There was also a significant cross-level interaction between individual and family contexts for frequency but not quantity of drinking.
Results of this study indicate a potential causal effect of age at drinking onset on adult alcohol involvement as well as the importance of examining both individual and contextual effects in discordant twin studies.
先前的研究已经证实,饮酒起始年龄较早与成年后酒精摄入量增加之间存在关联,但尚未确定这是否存在因果效应。本研究采用多层次不相符双胞胎设计,检验了饮酒起始年龄对成年后饮酒频率和饮酒量的个体和环境影响,以及这些影响之间的相互作用。
参与者为来自澳大利亚双胞胎登记处的 4194 对同性双胞胎(2264 对同卵双胞胎,1924 对异卵双胞胎;2270 名女性;平均年龄= 29.9 岁),他们完成了电话访谈,其中包括对饮酒起始年龄以及过去一年的饮酒频率和饮酒量的评估。使用全样本数据和仅同卵双胞胎数据估计了多层次模型。估计了个体(双胞胎内比较)和家庭环境(双胞胎间比较)的效应。
首次饮酒年龄与成年早期的饮酒频率(r=-.16)和饮酒量(r=-.12)相关。饮酒起始年龄的个体(因果)和家庭环境效应预测了以后的成年饮酒频率和饮酒量。在饮酒频率方面,还存在个体和家庭环境之间显著的跨层次交互作用,但在饮酒量方面则没有。
本研究结果表明,饮酒起始年龄对成年后酒精摄入可能存在因果效应,同时也表明在不相符双胞胎研究中,不仅要检验个体效应,还要检验环境效应。