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腰椎小关节方向与骨关节炎:一项横断面研究。

Lumbar facet joint orientation and osteoarthritis: a cross-sectional study.

作者信息

Linov Lina, Klindukhov Alexander, Li Ling, Kalichman Leonid

机构信息

Department of Radiology, Barzilai Medical Center, Ashkelon, Israel.

出版信息

J Back Musculoskelet Rehabil. 2013;26(4):421-6. doi: 10.3233/BMR-130401.

Abstract

BACKGROUND AND OBJECTIVE

The association between facet orientation, tropism (asymmetry of the facet angles) and facet joint osteoarthritis (OA) has been previously reported, however, it is necessary to confirm the association in other samples. Our aim was to evaluate the association between facet orientation, tropism, and facet joint OA in an Israeli sample.

METHODS

One hundred and fifty low back and abdominal CTs of 82 males (mean age 61.74 ± 12.99) and 68~females (mean age 59.51 ± 11.74,) were evaluated in a cross-sectional study. Facet joint OA was evaluated at the L4-L5 spinal level using a 4-graded scale. The association between facet joint OA, facet orientation and tropism was examined using multiple logistic regressions adjusted for age and sex.

RESULTS

Facet orientation showed a statistically significant association with facet joint OA on the right side (p=0.009) and in a model where both sides were combined (p=0.003). Facet joints with OA were more sagittally oriented. Tropism was not associated with facet joint OA on either side (p=0.251 for right and 0.609 for the left side), or in a combination of both sides (p=0.482).

CONCLUSIONS

We confirm a significant association between sagittal orientation and OA of the lumbar facet joints at level L4-L5. Facet tropism was not associated with facet joint OA. Additional longitudinal studies are needed to understand the causal relationship between facet joint orientation and OA.

摘要

背景与目的

小关节方向、关节不对称(小关节角度不对称)与小关节骨关节炎(OA)之间的关联此前已有报道,然而,有必要在其他样本中证实这种关联。我们的目的是评估以色列样本中小关节方向、关节不对称与小关节骨关节炎之间的关联。

方法

在一项横断面研究中,对82名男性(平均年龄61.74±12.99岁)和68名女性(平均年龄59.51±11.74岁)的150份腰椎和腹部CT进行了评估。使用4级量表在L4-L5脊柱节段评估小关节骨关节炎。采用经年龄和性别调整的多元逻辑回归分析小关节骨关节炎、小关节方向与关节不对称之间的关联。

结果

小关节方向在右侧(p=0.009)以及两侧合并的模型中(p=0.003)与小关节骨关节炎存在统计学显著关联。患有骨关节炎的小关节矢状位方向更明显。关节不对称在两侧(右侧p=0.251,左侧p=0.609)或两侧合并(p=0.482)时均与小关节骨关节炎无关。

结论

我们证实了L4-L5节段腰椎小关节矢状位方向与骨关节炎之间存在显著关联。小关节不对称与小关节骨关节炎无关。需要进一步的纵向研究来了解小关节方向与骨关节炎之间的因果关系。

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