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Nucleotides modulate synoviocyte proliferation and osteoclast differentiation in macrophages with potential implications for rheumatoid arthritis.核苷酸调节巨噬细胞中滑膜细胞增殖和破骨细胞分化，对类风湿性关节炎可能具有潜在影响。
3 Biotech. 2021 Dec;11(12):504. doi: 10.1007/s13205-021-03052-8. Epub 2021 Nov 19.
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Adenosine deaminase modulates metabolic remodeling and orchestrates joint destruction in rheumatoid arthritis.腺苷脱氨酶调节代谢重塑并协调类风湿关节炎中的关节破坏。
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本文引用的文献

1
Role of the P2Y13 receptor in the differentiation of bone marrow stromal cells into osteoblasts and adipocytes.P2Y13受体在骨髓基质细胞向成骨细胞和脂肪细胞分化中的作用。
Stem Cells. 2013 Dec;31(12):2747-58. doi: 10.1002/stem.1411.
2
Lysophosphatidic acid stimulates osteoclast fusion through OC-STAMP and P2X7 receptor signaling.溶血磷脂酸通过 OC-STAMP 和 P2X7 受体信号促进破骨细胞融合。
J Bone Miner Metab. 2014 Mar;32(2):110-22. doi: 10.1007/s00774-013-0470-9. Epub 2013 Apr 27.
3
Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors.冲击波通过释放 ATP 和激活 P2X7 受体诱导人骨髓间充质干细胞的成骨分化。
Stem Cells. 2013 Jun;31(6):1170-80. doi: 10.1002/stem.1356.
4
The P2Y13 receptor regulates extracellular ATP metabolism and the osteogenic response to mechanical loading.P2Y13 受体调节细胞外 ATP 代谢和机械加载的成骨反应。
J Bone Miner Res. 2013 Jun;28(6):1446-56. doi: 10.1002/jbmr.1877.
5
The sixth sense: hematopoietic stem cells detect danger through purinergic signaling.第六感：造血干细胞通过嘌呤能信号转导感知危险。
Blood. 2012 Sep 20;120(12):2365-75. doi: 10.1182/blood-2012-04-422378. Epub 2012 Jul 11.
6
A novel role for P2X7 receptor signalling in the survival of mouse embryonic stem cells.P2X7 受体信号在小鼠胚胎干细胞存活中的新作用。
Cell Signal. 2012 Mar;24(3):770-8. doi: 10.1016/j.cellsig.2011.11.012. Epub 2011 Nov 18.
7
The P2X7 receptor and Pannexin-1 are both required for the promotion of multinucleated macrophages by the inflammatory cytokine GM-CSF.P2X7 受体和 Pannexin-1 对于炎症细胞因子 GM-CSF 促进多核巨细胞的形成都是必需的。
J Immunol. 2011 Oct 1;187(7):3878-87. doi: 10.4049/jimmunol.1002780. Epub 2011 Aug 24.
8
Shockwaves increase T-cell proliferation and IL-2 expression through ATP release, P2X7 receptors, and FAK activation.冲击波通过三磷酸腺苷（ATP）释放、嘌呤能 P2X7 受体和粘着斑激酶（FAK）激活来增加 T 细胞增殖和白细胞介素-2（IL-2）的表达。
Am J Physiol Cell Physiol. 2010 Mar;298(3):C457-64. doi: 10.1152/ajpcell.00342.2009. Epub 2009 Nov 4.
9
Lysophosphatidic acid signaling promotes proliferation, differentiation, and cell survival in rat growth plate chondrocytes.溶血磷脂酸信号传导促进大鼠生长板软骨细胞的增殖、分化和细胞存活。
Biochim Biophys Acta. 2009 May;1793(5):836-46. doi: 10.1016/j.bbamcr.2009.01.020. Epub 2009 Feb 21.
10
Regulation of osteoblast differentiation by transcription factors.转录因子对成骨细胞分化的调控
J Cell Biochem. 2006 Dec 1;99(5):1233-9. doi: 10.1002/jcb.20958.

Role of the P2X7 receptor in the osteogenic differentiation of mesenchymal cells and in osteoclast fusion : presented by: Maria P. Abbracchio.

作者信息

Wang Ning, Gartland Alison

机构信息

The Mellanby Centre for Bone Research, Department of Human Metabolism, The University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.

出版信息

Purinergic Signal. 2013 Sep;9(3):281-4. doi: 10.1007/s11302-013-9384-1.

DOI:10.1007/s11302-013-9384-1
PMID:23949014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3757136/
Abstract
摘要