Department of General Intensive Care, University Hospital of Liege, Domaine Universitaire du Sart-Tilman, 4000, Liège, Belgium,
Curr Infect Dis Rep. 2013 Oct;15(5):380-4. doi: 10.1007/s11908-013-0359-8.
Much controversy exists about pneumonia in intensive care-especially, ventilator-associated pneumonia (VAP)-about its diagnosis and its attributable mortality. A better consensus exists about its prevention and its treatment. VAP occurs in already critically ill patients, and the relationship between preexisting organ dysfunction or failures and the severity of VAP has been recently highlighted. The role of the underlying disease should be considered as dominant, and this fact explains the paradox that exists between the high mortality of VAP and the relative minor effect of prevention measures on mortality.
关于重症监护病房中的肺炎(尤其是呼吸机相关性肺炎,VAP),存在很多争议,主要涉及到它的诊断和归因死亡率。人们对其预防和治疗已经达成了更好的共识。VAP 发生在已经病重的患者中,近期强调了先前存在的器官功能障碍或衰竭与 VAP 严重程度之间的关系。基础疾病的作用应被视为主要因素,这一事实解释了 VAP 高死亡率与预防措施对死亡率相对较小影响之间存在的悖论。