Zisova Liliya Georgieva, Dobrev Hristo Petrov, Tchernev Georgi, Semkova Kristina, Aliman Anastasia Atanasova, Chorleva Kristina Ivanova, Chapanova Antonina Teneva, Vutova Nina Ivanova, Wollina Uwe
Dermatology and Venereology Department, Medical University, Plovdiv, Bulgaria,
Wien Med Wochenschr. 2013 Dec;163(23-24):549-55. doi: 10.1007/s10354-013-0230-4. Epub 2013 Aug 15.
Fungal infections of the skin are a common condition, usually easy to diagnose and treat. When the infection is clinically mimicking another cutaneous disorder or when the clinical presentation is modified by the use of inappropriate treatment, it is referred to as tinea atypica or tinea incognito.We report a series of nine cases of patients with tinea atypica, imitating and diagnosed initially as different skin diseases. Two patients were defined as pyoderma in the facial and pubic regions (caused respectively by Trichophyton mentagrophytes var. mentagrophytes and Microsporum canis) and one as herpes zoster ophthalmicus (caused by Trichophyton rubrum). Six additional patients were initially misdiagnosed: (1) Plaque-like formation of the skin misdiagnosed as an impetiginized eczema (with isolated agent Trichophyton verrucosum). (2) A rare form of skin infection of the hand caused by T. rubrum, imitating clinically cutaneous infection with tuberculum mulgentium. (3) Rosacea-like dermatitis with an isolated agent Fusarium. (4) A patient with the typical clinical symptoms of seborrheic dermatitis of the face (and with isolated T. rubrum as a causative agent). (5) Another patient presented with a widespread folliculitis by Trichophyton mentagrophytes. (6) In a patient with bullous pemphigoid and immunosuppression pemphigoid-like eruptions were caused by Malassezia pachydermatis and T. rubrum. The diagnosis in the presented cases was based on direct microscopic examination with KOH and a culture on Sabouraud agar.After the diagnosis of tinea, treatment with topical and systemic antifungal agents was administrated, followed by complete clinical remissions in all cases.The clinical manifestations of tinea atypica can mimic a large number of other dermatoses, which often leads to misdiagnosing, and as a consequence--to serious difficulties in the management of clinical symptoms and in offering appropriate therapy.
皮肤真菌感染是一种常见病症,通常易于诊断和治疗。当感染在临床上类似另一种皮肤病,或临床表现因使用不恰当治疗而改变时,就被称为非典型癣或隐匿性癣。我们报告了一系列9例非典型癣患者,最初被误诊并诊断为不同的皮肤病。2例患者被诊断为面部和耻骨区脓疱病(分别由须癣毛癣菌和犬小孢子菌引起),1例被诊断为眼部带状疱疹(由红色毛癣菌引起)。另外6例患者最初被误诊:(1)皮肤斑块状形成被误诊为脓疱化湿疹(病原菌为疣状毛癣菌)。(2)一种罕见的手部皮肤感染由红色毛癣菌引起,临床上类似皮肤结核感染。(3)玫瑰痤疮样皮炎,病原菌为镰刀菌。(4)1例患者有面部脂溢性皮炎的典型临床症状(病原菌为红色毛癣菌)。(5)另1例患者出现广泛的须癣毛癣菌毛囊炎。(6)1例大疱性类天疱疮且免疫抑制患者出现类似类天疱疮的皮疹,由厚皮马拉色菌和红色毛癣菌引起。本病例系列的诊断基于氢氧化钾直接显微镜检查和沙氏琼脂培养基培养。诊断为癣后,给予局部和全身抗真菌药物治疗,所有病例随后均临床完全缓解。非典型癣的临床表现可模仿大量其他皮肤病,这常导致误诊,进而在临床症状管理和提供适当治疗方面造成严重困难。