Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270, Dong'an Road, Xuhui District, Shanghai, China.
Ann Nucl Med. 2013 Dec;27(10):931-4. doi: 10.1007/s12149-013-0761-1. Epub 2013 Aug 15.
A 54-year-old metastatic breast cancer patient who had undergone chemotherapy and radiotherapy was transferred to our hospital for further treatment. We utilized (18)F-fluoroestradiol (FES) to assess the estrogen receptor (ER) status of metastatic lesions. Interestingly, high accumulation of (18)F-FES in pneumonia caused by radiation was detected. Hence, this draws oncologists' attention to the possible false-positive result of (18)F-FES, which may lead to inappropriate endocrine therapy.
一位 54 岁的转移性乳腺癌患者，曾接受化疗和放疗，转至我院进一步治疗。我们使用 (18)F-氟雌二醇 (FES) 评估转移性病变的雌激素受体 (ER) 状态。有趣的是，在放疗引起的肺炎中检测到 (18)F-FES 的高蓄积。因此，这引起了肿瘤学家对 (18)F-FES 可能出现假阳性结果的关注，这可能导致不适当的内分泌治疗。
